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Literature summary for 1.1.1.44 extracted from
- 6-Phosphogluconate dehydrogenase from Candida utilis (1975), Methods Enzymol., 41, 237-240.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Cyberlindnera jadinii |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.02 | - |
NADP+ | - |
Cyberlindnera jadinii |  |
| 0.054 | - |
6-phosphogluconate | - |
Cyberlindnera jadinii | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-phospho-D-gluconate + NADP+ | Cyberlindnera jadinii | - |
D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cyberlindnera jadinii | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Cyberlindnera jadinii |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 41.8 | - |
- |
Cyberlindnera jadinii |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, stable for several days, as an (NH4)2SO4 suspension stable for several months without any loss of enzyme activity | Cyberlindnera jadinii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-deoxy-6-phosphogluconate + NADP+ | - |
Cyberlindnera jadinii | 3-oxo-2-deoxy-6-phosphogluconate + NADPH | - |
r | |
| 3-oxo-2-deoxy-6-phosphogluconate + NADP+ | reaction requires presence of NADPH, but the reduced coenzyme does not play a redox role | Cyberlindnera jadinii | 1-deoxyribulose 5-phosphate + CO2 + NADPH | - |
? | |
| 3-oxo-2-deoxy-6-phosphogluconate + NADPH | - |
Cyberlindnera jadinii | 2-deoxy-6-phosphogluconate + NADP+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | - |
Cyberlindnera jadinii | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| ribulose 5-phosphate + H2O + NADPH | tritium exchange reaction between tritiated ribulose 5-phosphate and water, reaction requires presence of NADPH, but the reduced coenzyme does not play a redox role | Cyberlindnera jadinii | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Cyberlindnera jadinii |
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Release 2023.1 (January 2023)
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