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Literature summary for 1.1.1.43 extracted from

  • Hisar, O.; Sönmez, A.; Beydemir, A.; Hisar, A.; Yanik, T.; Cronin, T.
    Kinetic behaviour of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in different tissues of rainbow trout (Oncorhynchus mykiss) exposed to non-lethal concentrations of cadmium (2009), Acta Vet. Brno, 78, 179-185.
No PubMed abstract available
Search for more literature for 1.1.1.43

Metals/Ions

Metals/Ions Comment Organism Structure
Cd2+ the activity of 6PGD is stimulated after three days in the liver at a dose of 1 mg/l Cd and on the first day in gill, liver and kidney tissues at doses of 3 and 5 mg/l Cd. The stimulation effect of the 5 mg/l dose of Cd on G6PD and 6PGD enzyme activities is significantly diminished Oncorhynchus mykiss

Organism

Organism UniProt Comment Textmining
Oncorhynchus mykiss
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gill
-
 Oncorhynchus mykiss
-
kidney
-
 Oncorhynchus mykiss
-
liver
-
 Oncorhynchus mykiss
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-phospho-D-gluconate + NADP+
-
 Oncorhynchus mykiss 6-phospho-2-dehydro-D-gluconate + NADPH + H+
-
 ?

Synonyms

Synonyms Comment Organism
6PGDH
-
 Oncorhynchus mykiss

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Oncorhynchus mykiss

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Oncorhynchus mykiss

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Oncorhynchus mykiss

General Information

General Information Comment Organism
physiological function 6PGD enzymes functions to protect against cadmium toxicity Oncorhynchus mykiss