Protein Variants | Comment | Organism |
---|---|---|
K362H | the mutant enzyme displays a considerable elevation in Km for NADP+, and the kcat for NAD+ value is elevated compared to the wild-type enzyme | Ascaris suum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Ascaris suum | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | Ascaris suum | - |
pyruvate + CO2 + NADH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ascaris suum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | - |
Ascaris suum | pyruvate + CO2 + NADH | - |
r |
Synonyms | Comment | Organism |
---|---|---|
m-NAD-ME | - |
Ascaris suum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | His362 is involved in NAD+-specific catalysis of NAD-ME, and residue 314 may interact with the bisphosphate of the NAD+ moiety, structure analysis, overview | Ascaris suum |