Any feedback?
Literature summary for 1.1.1.37 extracted from
- Rat liver mitochondrial malate dehydrogenase: Purification, kinetic properties, and role in ethanol metabolism (1991), Arch. Biochem. Biophys., 290, 191-196.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-malate | - |
Homo sapiens |  |
| L-malate | - |
Rattus norvegicus | |
| L-malate | - |
Sus scrofa | |
| oxaloacetate | - |
Rattus norvegicus | |
| oxaloacetate | - |
Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
| cytosol | - |
Rattus norvegicus | 5829 | - |
| cytosol | - |
Sus scrofa | 5829 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| mitochondrion | - |
Sus scrofa | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| malate + NAD+ | Homo sapiens | - |
oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | Rattus norvegicus | - |
oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | Sus scrofa | - |
oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | Rattus norvegicus Sprague-Dawley | - |
oxaloacetate + NADH + H+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
| Rattus norvegicus | - |
rat | - |
| Rattus norvegicus | - |
Sprague-Dawley | - |
| Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley | - |
| Sus scrofa | - |
pig | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Sus scrofa | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 68 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-malate + NAD+ | - |
Homo sapiens | oxaloacetate + NADH + H+ | - |
r | |
| (S)-malate + NAD+ | - |
Rattus norvegicus | oxaloacetate + NADH + H+ | - |
r | |
| (S)-malate + NAD+ | - |
Sus scrofa | oxaloacetate + NADH + H+ | - |
r | |
| (S)-malate + NAD+ | - |
Rattus norvegicus Sprague-Dawley | oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | - |
Homo sapiens | oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | - |
Rattus norvegicus | oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | - |
Sus scrofa | oxaloacetate + NADH + H+ | - |
r | |
| malate + NAD+ | - |
Rattus norvegicus Sprague-Dawley | oxaloacetate + NADH + H+ | - |
r | |
| oxaloacetate + NADH | - |
Homo sapiens | L-malate + NAD+ | - |
r | |
| oxaloacetate + NADH | - |
Rattus norvegicus | L-malate + NAD+ | - |
r | |
| oxaloacetate + NADH | - |
Sus scrofa | L-malate + NAD+ | - |
r | |
| oxaloacetate + NADH | - |
Rattus norvegicus Sprague-Dawley | L-malate + NAD+ | - |
r | |
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