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Literature summary for 1.1.1.34 extracted from

  • Zhang, M.; Liu, H.; Wang, Q.; Liu, S.; Zhang, Y.
    The 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5 gene from Malus domestica enhances oxidative stress tolerance in Arabidopsis thaliana (2020), Plant Physiol. Biochem., 146, 269-277 .
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Arabidosis thaliana Malus domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ Malus domestica
-
 (R)-mevalonate + CoA + 2 NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Malus domestica
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Malus domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
-
 Malus domestica (R)-mevalonate + CoA + 2 NADP+
-
 ?

Synonyms

Synonyms Comment Organism
3-hydroxy-3-methylglutaryl-coenzyme A reductase 5
-
 Malus domestica
HMGR5
-
 Malus domestica

Expression

Organism Comment Expression
Malus domestica after oxidative stress treatment with 0.1 mM methyl viologen, the expression level of isoform HMGR5 is up-regulated significantly at 24 h up

General Information

General Information Comment Organism
physiological function overexpression of isoform HMGR5 enhances tolerance to oxidative stress by maintaining photosynthesis and scavenging reactive oxygen species in transgenic Arabidopsis thaliana Malus domestica