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Literature summary for 1.1.1.318 extracted from

  • Koeduka, T.; Fridman, E.; Gang, D.; Vassao, D.; Jackson, B.; Kish, C.; Orlova, I.; Spassova, S.; Lewis, N.; Noel, J.; Baiga, T.; Dudareva, N.; Pichersky, E.
    Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester (2006), Proc. Natl. Acad. Sci. USA, 103, 10128-10133.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative expression analysis Ocimum basilicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
coniferyl acetate + NADPH + H+ Ocimum basilicum
-
 eugenol + acetate + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Ocimum basilicum Q15GI4
-
-

Reaction

Reaction Comment Organism Reaction ID
eugenol + a carboxylate + NADP+ = a coniferyl ester + NADPH + H+ reaction mechanism, overview Ocimum basilicum
a

Source Tissue

Source Tissue Comment Organism Textmining
glandular trichome
-
 Ocimum basilicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coniferyl acetate + NADPH + H+
-
 Ocimum basilicum eugenol + acetate + NADP+
-
 ?
coniferyl acetate + NADPH + H+
-
 Ocimum basilicum eugenol + acetate + NADP+ GC-MS analysis product analysis ?

Synonyms

Synonyms Comment Organism
EGS
-
 Ocimum basilicum
EGS1
-
 Ocimum basilicum
eugenol synthase 1
-
 Ocimum basilicum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
28
-
 assay at Ocimum basilicum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 assay at Ocimum basilicum

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Ocimum basilicum

General Information

General Information Comment Organism
evolution the phenylpropene-forming eugenol synthase, EGS, belongs to a structural family of NADPH-dependent reductases that also includes isoeugenol synthase, IGS, pinoresinol-lariciresinol reductase, isoflavone reductase, and phenylcoumaran benzylic ether reductase, evolution and function of EGS1 and IGS1, overview Ocimum basilicum