Literature summary for 1.1.1.303 extracted from

Zhang, L.; Cao, C.; Jiang, R.; Xu, H.; Xue, F.; Huang, W.; Ni, H.; Gao, J.
Production of R,R-2,3-butanediol of ultra-high optical purity from Paenibacillus polymyxa ZJ-9 using homologous recombination (2018), Biores. Technol., 261, 272-278 .

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Protein Variants

Protein Variants	Comment	Organism
additional information	knockout of diacetyl reductase (DAR) gene dudA in Paenibacillus polymyxa strain ZJ-9 via homologous recombination between the genome and the previously constructed targeting vector pRN5101-L'C in a process based on homologous single-crossover. Disruption mutant Paenibacillus polymyxa ZJ-9-DELTAdudA is used for production of (R,R)-2,3-butanediol of ultra-high optical purity, and without parts of meso-2,3-butanediol, through (R,R)-butanediol dehydrogenase (EC 1.1.1.4). Paenibacillus polymyxa is a microorganism with a reported potential for the industrial production of (R,R)-2,3-butanediol. Gene dudA, the gene encoding DAR, is the key factor responsible for the formation of meso-2,3-butanediol, thus reducing the purity of (R,R)-2,3-butanediol	Paenibacillus polymyxa

Organism

Organism	UniProt	Comment	Textmining
Paenibacillus polymyxa	V9NF79	-	-
Paenibacillus polymyxa ZJ-9	V9NF79	-	-

Synonyms

Synonyms	Comment	Organism
DAR	-	Paenibacillus polymyxa
dudA	-	Paenibacillus polymyxa

General Information

General Information	Comment	Organism
physiological function	dudA, the gene encoding DAR, is the key factor responsible for the formation of meso-2,3-butanediol	Paenibacillus polymyxa

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Release 2023.1 (January 2023)