Literature summary for 1.1.1.303 extracted from

Gonzalez, E.; Fernandez, M.R.; Larroy, C.; Sola, L.; Pericas, M.A.; Pares, X.; Biosca, J.A.
Characterization of a (2R,3R)-2,3-butaendiol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product (2000), J. Biol. Chem., 275, 35876-35885.

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Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P39714	bifunctional diacetyl reductase and (R)-2,3-butanediol dehydrogenase	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
diacetyl + NADH + H+	51.4% of the (R)-2,3-butanediol dehydrogenase activity with substrate acetoin	Saccharomyces cerevisiae	(R)-acetoin + NAD+	-	ir

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Saccharomyces cerevisiae

General Information

General Information	Comment	Organism
physiological function	gene disruption is not lethal. Disrupted strains can grow on 2,3-butanediol, but to a lesser cell density than wild-type	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)