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Literature summary for 1.1.1.303 extracted from

  • Heidlas, J.; Tressl, R.
    Purification and characterization of a (R)-2,3-butanediol dehydrogenase from Saccharomyces cerevisiae (1990), Arch. Microbiol., 154, 267-273.
    View publication on PubMed
Search for more literature for 1.1.1.303

Activating Compound

Activating Compound Comment Organism Structure
Mg2+ activation, (R)-2,3-butanediol dehydrogenase activity Saccharomyces cerevisiae
Mn2+ activation, (R)-2,3-butanediol dehydrogenase activity Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
dipicolinate inhibition, (R)-2,3-butanediol dehydrogenase activity Saccharomyces cerevisiae
EDTA inhibition, (R)-2,3-butanediol dehydrogenase activity Saccharomyces cerevisiae
o-phenanthroline inhibition, (R)-2,3-butanediol dehydrogenase activity Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 4 * 35000, SDS-PAGE Saccharomyces cerevisiae
140000
-
 gel filtration Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 bifunctional diacetyl reductase and (R)-2,3-butanediol dehydrogenase
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-cyclohexanedione + NADH + H+ 5% of the (R)-2,3-butanediol dehydrogenase activity with substrate acetoin Saccharomyces cerevisiae (R)-2-hydroxy-1-cyclohexanone + NAD+
-
 ir
2,3-pentanedione + NADH + H+ 7% of the (R)-2,3-butanediol dehydrogenase activity with substrate acetoin Saccharomyces cerevisiae (3R)-3-hydroxy-2-pentanone + NAD+
-
 ir
diacetyl + NADH + H+ 21% of the (R)-2,3-butanediol dehydrogenase activity with substrate acetoin Saccharomyces cerevisiae (R)-acetoin + NAD+
-
 ir
additional information enzyme is specific for NADH Saccharomyces cerevisiae ?
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 35000, SDS-PAGE Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
NADH enzyme is specific for NADH Saccharomyces cerevisiae