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Literature summary for 1.1.1.300 extracted from

  • Haeseleer, F.; Huang, J.; Lebiodas, L.; Saari, J.C.; Palczewski, K.
    Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal (1998), J. Biol. Chem., 273, 21790-21799.
    View publication on PubMed
Search for more literature for 1.1.1.300

Cloned(Commentary)

Cloned (Comment) Organism
full-length short-chain dehydrogenase/reductase cDNA expressed in Escherichia coli, truncated cDNA expressed in SF9 insect cells, enzyme belongs to the short-chain dehydrogenase/reductase superfamily Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
all-trans-retinal + NADPH + H+ Homo sapiens
-
 all-trans-retinol + NADP+
-
 r
all-trans-retinal + NADPH + H+ Homo sapiens involved in the regeneration of bleached visual pigments in photoreceptor cells, involved in retinol metabolism outside of photoreceptor cells all-trans-retinol + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O75911
-
-

Source Tissue

Source Tissue Comment Organism Textmining
photoreceptor cone photoreceptor cell Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
all-trans-retinal + NAD(P)H + H+
-
 Homo sapiens all-trans-retinol + NAD(P)+
-
 ?
all-trans-retinal + NAD(P)H + H+
-
 Homo sapiens all-trans-retinol + NAD(P)+
-
 r
all-trans-retinal + NADPH + H+
-
 Homo sapiens all-trans-retinol + NADP+
-
 r
all-trans-retinal + NADPH + H+ involved in the regeneration of bleached visual pigments in photoreceptor cells, involved in retinol metabolism outside of photoreceptor cells Homo sapiens all-trans-retinol + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
all-trans-retinol dehydrogenase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens