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Literature summary for 1.1.1.3 extracted from

  • Cahyanto, M.N.; Kawasaki, H.; Nagashio, M.; Fujiyama, K.; Seki, T.
    Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum (2006), Microbiology, 152, 105-112.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Lactiplantibacillus plantarum

Inhibitors

Inhibitors Comment Organism Structure
additional information Thr does not inhibit homoserine dehydrogenase 1 Lactiplantibacillus plantarum
Thr 90% inhibition of homoserine dehydrogenase 2 at 10 mM Lactiplantibacillus plantarum

Organism

Organism UniProt Comment Textmining
Lactiplantibacillus plantarum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate 4-semialdehyde + NADPH + H+
-
Lactiplantibacillus plantarum L-homoserine + NADP+
-
?
L-aspartate 4-semialdehyde + NADPH + H+
-
Lactiplantibacillus plantarum NCIMB 8826 L-homoserine + NADP+
-
?

Synonyms

Synonyms Comment Organism
homoserine dehydrogenase 1
-
Lactiplantibacillus plantarum
homoserine dehydrogenase 2
-
Lactiplantibacillus plantarum

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Lactiplantibacillus plantarum