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Literature summary for 1.1.1.3 extracted from

  • Pavagi, S.; Kochhar, S.; Kochhar, V.K.; Sane, P.V.
    Purification and characterization of homoserine dehydrogenase from spinach leaves (1995), Biochem. Mol. Biol. Int., 36, 649-658.
    View publication on PubMed
Search for more literature for 1.1.1.3

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin in the presence of above 0.1 mM Ca2+ Spinacia oleracea

Inhibitors

Inhibitors Comment Organism Structure
aspartate
-
 Spinacia oleracea
EGTA
-
 Spinacia oleracea
L-cysteine
-
 Spinacia oleracea
L-threonine
-
 Spinacia oleracea
lysine
-
 Spinacia oleracea
methionine
-
 Spinacia oleracea
Trifluoperazine
-
 Spinacia oleracea

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 DL-aspartate 4-semialdehyde
-
 Spinacia oleracea
0.3
-
 NADH
-
 Spinacia oleracea
0.5
-
 L-aspartate 4-semialdehyde
-
 Spinacia oleracea

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 4 * 55000, SDS-PAGE Spinacia oleracea
220000
-
 gel filtration Spinacia oleracea

Organism

Organism UniProt Comment Textmining
Spinacia oleracea
-
 spinach
-
Spinacia oleracea
-
 also shows aspartase kinase activity
-

Purification (Commentary)

Purification (Comment) Organism
-
 Spinacia oleracea

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Spinacia oleracea
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DL-aspartate 4-semialdehyde + NADPH + H+
-
 Spinacia oleracea L-homoserine + NADP+
-
 r
L-aspartate 4-semialdehyde + NAD(P)H
-
 Spinacia oleracea L-homoserine + NAD(P)+
-
 r
L-homoserine + NAD(P)+
-
 Spinacia oleracea L-aspartate 4-semialdehyde + NAD(P)H
-
 r

Subunits

Subunits Comment Organism
tetramer 4 * 55000, SDS-PAGE Spinacia oleracea