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Literature summary for 1.1.1.29 extracted from
- Glyoxylate reductase/hydroxypyruvate reductase: a novel prognostic marker for hepatocellular carcinoma patients after curative resection (2013), Pathobiology, 80, 155-162.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | glyoxylate reductase/hydroxypyruvate reductase is a prognostic marker for hepatocellular carcinoma patients after curative resection | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydroxypyruvate + NADH + H+ | Homo sapiens | - |
D-glycerate + NAD+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEP-3B cell | - |
Homo sapiens | - |
| Hep-G2 cell | - |
Homo sapiens | - |
| hepatocellular carcinoma cell | - |
Homo sapiens | - |
| Huh-7 cell | - |
Homo sapiens | - |
| liver | - |
Homo sapiens | - |
| SMMC-7721 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydroxypyruvate + NADH + H+ | - |
Homo sapiens | D-glycerate + NAD+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GRHPR | bifunctional enzyme with glyoxylate reductase and hydroxypyruvate reductase activities | Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Homo sapiens | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | enzyme expression is decreased or lost in hepatocellular carcinoma | down |
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