Literature summary for 1.1.1.284 extracted from

Patra, S.K.; Bag, P.K.; Ghosh, S.
Nitrosative stress response in Vibrio cholerae: role of S-nitrosoglutathione reductase (2017), Appl. Biochem. Biotechnol., 182, 871-884.

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Inhibitors

Inhibitors	Comment	Organism	Structure
nitroprusside	GSNO reductase activity is about two- to threefold decreased following a 2h stress treatment with 1 mM sodium nitroprusside	Vibrio cholerae serotype O1

Organism

Organism	UniProt	Comment	Textmining
Vibrio cholerae serotype O1	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
nitrosylation	GSNO reductase activity is regulated by posttranslational modification through S-nitrosylation under in vitro conditions which can be reversed by dithiothreitol	Vibrio cholerae serotype O1

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-nitrosoglutathione + NADH + H+	-	Vibrio cholerae serotype O1	? + NAD+	-	?

General Information

General Information	Comment	Organism
physiological function	biofilm formation remains unaffected under nitrosative stress in Vibrio cholerae	Vibrio cholerae serotype O1

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Release 2023.1 (January 2023)