Literature summary for 1.1.1.283 extracted from

Murata, K.; Fukuda, Y.; Shimosaka, M.; Watanabe, K.; Saikusa, T.; Kimura, A.
Phenotypic character of the methylglyoxal resistance gene in Saccharomyces cerevisiae: expression in Escherichia coli and application to breeding wild-type yeast strains (1985), Appl. Environ. Microbiol., 50, 1200-1207.

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Cloned(Commentary)

Cloned (Comment)	Organism
similar enzyme with NADPH-requirement for methylglyoxal reduction, that is inactive with NAD+, NADH and NADP+	Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
methylglyoxal + NADPH	Saccharomyces cerevisiae	-	lactaldehyde + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	similar enzyme with NADPH-requirement for methylglyoxal reduction, that is inactive with NAD+, NADH and NADP+	-

Reaction

Reaction	Comment	Organism	Reaction ID
(S)-lactaldehyde + NADP+ = 2-oxopropanal + NADPH + H+	similar enzyme with NADPH-requirement for methylglyoxal reduction, that is inactive with NAD+, NADH and NADP+	Saccharomyces cerevisiae	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
methylglyoxal + NADPH	-	Saccharomyces cerevisiae	lactaldehyde + NADP+	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)