Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | 3beta-HSD/isomerase activity only occurs following lactonization of the steroidal ring-D | Aspergillus tamarii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | presence of C-7 allylic hydroxylation, in either epimeric form, inhibits 3beta-HSD/isomerase activity | Aspergillus tamarii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus tamarii | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3beta-hydroxy-16alpha,17alpha-epoxypregn-5-en-20-one + NADP+ | is metabolized through the putative 3beta-HSD/isomerase pathway | Aspergillus tamarii | ? | - |
? | |
dehydroepiandrosterone + NADP+ | can also enter a minor hydroxylation pathway | Aspergillus tamarii | ? | - |
? | |
dehydroepiandrosterone + NADP+ | can also enter a minor hydroxylation pathway | Aspergillus tamarii KITA | ? | - |
? | |
pregnenolone + NADP+ | is metabolized through the putative 3beta-HSD/isomerase pathway | Aspergillus tamarii | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3beta-HSD/isomerase | - |
Aspergillus tamarii |
3beta-hydroxy-steroid dehydrogenase/DELTA5-DELTA4 isomerase | - |
Aspergillus tamarii |