Literature summary for 1.1.1.27 extracted from

Lee, S.; Koppensteiner, R.; Kopp, C.W.; Gremmel, T.
alpha-Hydroxybutyrate dehydrogenase is associated with atherothrombotic events following infrainguinal angioplasty and stenting (2019), Sci. Rep., 9, 18200 .

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Application

Application	Comment	Organism
medicine	HBDH is associated with atherothrombotic events in 83 stable patients undergoing infrainguinal angioplasty and stenting. HBDH levels at baseline are significantly higher in patients who subsequently developed the primary endpoint. HBDH can distinguish between patients without and with future atherothrombotic events. A HBDH concentration at/above 115 U/l is the best threshold to predict the composite endpoint, providing a sensitivity of 83.3% and a specificity of 71.4%, and is therefore defined as high HBDH. Ischemic events occur significantly more often in patients with high HBDH than in patients with lower HBDH levels	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
alpha-hydroxybutyrate dehydrogenase	-	Homo sapiens
HBDH	-	Homo sapiens

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Release 2023.1 (January 2023)