Cloned (Comment) | Organism |
---|---|
into expression plasmid pTUB8Myc-His-X-HX under the control of a modified tubulin promoter. Type I strain of Toxoplasma gondii RHDELTAHX transformed with plasmid. Transgenic parasites overexpressing LDH1 | Toxoplasma gondii |
into expression plasmid pTUB8Myc-His-X-HX under the control of a modified tubulin promoter. Type I strain of Toxoplasma gondii RHDELTAHX transformed with plasmid. Transgenic parasites overexpressing LDH2 | Toxoplasma gondii |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Toxoplasma gondii | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
39200 | - |
antibodies | Toxoplasma gondii |
39900 | - |
antibodies | Toxoplasma gondii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Toxoplasma gondii | P90613 | - |
- |
Toxoplasma gondii | Q27797 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bradyzoite | LDH2 | Toxoplasma gondii | - |
additional information | LDH1 is absent from bradyzoites | Toxoplasma gondii | - |
additional information | LDH2 is absent from tachyzoites | Toxoplasma gondii | - |
tachyzoite | - |
Toxoplasma gondii | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate + NADH | LDH1 has an important physiological function, in addition to being a glycolytic enzyme and differentiation marker. The enzymatic activity, growth, and virulence of tachyzoites are unaffected by the presence of the recombinant protein. Overexpression of LDH1 enhances the parasite's ability to differentiate | Toxoplasma gondii | L-lactate + NAD+ | - |
? | |
pyruvate + NADH | LDH2 has an important physiological function, in addition to being a glycolytic enzyme and differentiation marker. The enzymatic activity, growth, and virulence of tachyzoites are unaffected by the presence of the recombinant protein. Overexpression of LDH2 enhances the parasite's ability to differentiate | Toxoplasma gondii | L-lactate + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lactate dehydrogenase | - |
Toxoplasma gondii |
LDH1 | - |
Toxoplasma gondii |
LDH2 | - |
Toxoplasma gondii |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
under alkaline conditions the presence of the recombinant LDH protein increases the differentiation | Toxoplasma gondii |
additional information | - |
under alkaline conditions the presence of the recombinant LDH proteins increases the differentiation | Toxoplasma gondii |