Cloned (Comment) | Organism |
---|---|
overexpression in Escherichia coli | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-(phosphohydroxy)-L-threonine + NAD+ | Escherichia coli | involved in pyridoxal 5'-phosphate formation | 2-amino-3-oxo-4-phosphohydroxybutyrate + NADH | further condensation with 1-deoxy-D-xylulose-5-phosphate to form pyridoxal 5'-phosphate | r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to homogeneity, recombinant enzyme | Escherichia coli |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | pdxA gene product | Escherichia coli | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-(phosphohydroxy)-L-threonine + NAD+ | involved in pyridoxal 5'-phosphate formation | Escherichia coli | 2-amino-3-oxo-4-phosphohydroxybutyrate + NADH | further condensation with 1-deoxy-D-xylulose-5-phosphate to form pyridoxal 5'-phosphate | r |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.4 | - |
4-(phosphohydroxy)-L-threonine | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Escherichia coli |