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Literature summary for 1.1.1.237 extracted from

  • Petersen, M.; Alfermann, A.W.
    Two new enzymes of rosmarinic acid biosyntheses from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase (1988), Z. Naturforsch. C, 43, 501-504.
No PubMed abstract available
Search for more literature for 1.1.1.237

Activating Compound

Activating Compound Comment Organism Structure
ascorbic acid prevents oxidation of substrates Coleus scutellarioides
dithiothreitol
-
 Coleus scutellarioides

General Stability

General Stability Organism
sensitive to oxidation by light and oxygen Coleus scutellarioides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-(4-hydroxyphenyl)lactate + NAD+ Coleus scutellarioides biosynthesis of rosmarinic acid 4-hydroxyphenylpyruvate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Coleus scutellarioides
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate precipitation and Sephadex G25 column Coleus scutellarioides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dihydroxyphenylpyruvate + NADH + H+
-
 Coleus scutellarioides 3-(3,4-dihydroxyphenyl)lactate + NAD+
-
 ?
3-(4-hydroxyphenyl)lactate + NAD+ biosynthesis of rosmarinic acid Coleus scutellarioides 4-hydroxyphenylpyruvate + NADH + H+
-
 ?
4-hydroxyphenylpyruvate + NADH + H+
-
 Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NAD+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Coleus scutellarioides
NADP+ with lower activity than NAD+ Coleus scutellarioides