Literature summary for 1.1.1.22 extracted from

Li, N.; Chen, L.; Li, X.; Li, Q.; Zhang, W.; Takechi, K.; Takano, H.; Lin, X.
Overexpression of UDP-glucose dehydrogenase from Larix gmelinii enhances growth and cold tolerance in transgenic Arabidopsis thaliana (2017), Biol. Plant., 61, 95-105.

No PubMed abstract available

Cloned(Commentary)

Cloned (Comment)	Organism
the enzyme UGDH is encoded by two paralogous genes, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree, cloning in a plasmid with the CaMV 35S promoter, the GUS gene, and the nopaline synthase terminator, recombinant overexpression of UDP-glucose dehydrogenase from Larix gmelinii in Arabidopsis thaliana enhancing the content of soluble sugars and hemicelluloses and growth and cold tolerance in the transgenic plants, transfection via Agrobacterium tumefaciens strain LBA4404, realtime and reverse transcriptase PCR expression analysis. The transgenic plants show distinct phenotypes at different developmental stages, as compared to the wild-type, overview	Larix gmelinii

Cloned (Comment)

Organism

the enzyme UGDH is encoded by two paralogous genes, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree, cloning in a plasmid with the CaMV 35S promoter, the GUS gene, and the nopaline synthase terminator, recombinant overexpression of UDP-glucose dehydrogenase from Larix gmelinii in Arabidopsis thaliana enhancing the content of soluble sugars and hemicelluloses and growth and cold tolerance in the transgenic plants, transfection via Agrobacterium tumefaciens strain LBA4404, realtime and reverse transcriptase PCR expression analysis. The transgenic plants show distinct phenotypes at different developmental stages, as compared to the wild-type, overview

Larix gmelinii

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cell wall	-	Larix gmelinii	5618	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
UDP-alpha-D-glucose + 2 NAD+ + H2O	Larix gmelinii	-	UDP-alpha-D-glucuronate + 2 NADH + 2 H+	UDP-glucuronate is a key sugar nucleotide involved in biosynthesis of the plant cell wall	?

Organism

Organism	UniProt	Comment	Textmining
Larix gmelinii	A0A0E4FJQ1	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Larix gmelinii	-
additional information	the LgUGDH gene is expressed in all larch plant organs, primarily in the larch stems, in addition to its roots and leaves	Larix gmelinii	-
root	-	Larix gmelinii	-
stem	-	Larix gmelinii	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-alpha-D-glucose + 2 NAD+ + H2O	-	Larix gmelinii	UDP-alpha-D-glucuronate + 2 NADH + 2 H+	-	?
UDP-alpha-D-glucose + 2 NAD+ + H2O	-	Larix gmelinii	UDP-alpha-D-glucuronate + 2 NADH + 2 H+	UDP-glucuronate is a key sugar nucleotide involved in biosynthesis of the plant cell wall	?

Synonyms

Synonyms	Comment	Organism
UDP-glucose dehydrogenase	-	Larix gmelinii
UGDH	-	Larix gmelinii

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Larix gmelinii

General Information

General Information	Comment	Organism
metabolism	the enzyme participates in sucrose/polysaccharide metabolism and cell wall biosynthesis	Larix gmelinii
physiological function	the enzme synthesize UDP-glucuronate, a key sugar nucleotide involved in biosynthesis of the plant cell wall, the LgUGDH gene plays a role in controlling the biosynthesis of secondary cell walls	Larix gmelinii