Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.205 extracted from

  • Morrow, C.A.; Stamp, A.; Valkov, E.; Kobe, B.; Fraser, J.A.
    Crystallization and preliminary X-ray analysis of mycophenolic acid-resistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus (2010), Acta Crystallogr. Sect. F, 66, 1104-1107.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.205

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Cryptococcus neoformans
expression in Escherichia coli Cryptococcus gattii VGIII

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with NAD+ and IMP, to 2.5 A resolution. Space group I422 Cryptococcus neoformans
in complex with NAD+ and IMP, to 2.5 A resolution. Space group I422 Cryptococcus gattii VGIII

Inhibitors

Inhibitors Comment Organism Structure
Mycophenolic acid subtype MMRL2651 of Cryptococcus gattii is naturally resistant to inhibition by mycophenolic acid Cryptococcus gattii VGIII
Mycophenolic acid
-
 Cryptococcus neoformans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
 x * 58000, SDS-PAGE Cryptococcus neoformans
58000
-
 x * 58000, SDS-PAGE Cryptococcus gattii VGIII

Organism

Organism UniProt Comment Textmining
Cryptococcus gattii VGIII E3P6S3 MMRL2651, subtype naturally resistant to inhibition by mycophenolic acid
-
Cryptococcus neoformans
-
-
-
Cryptococcus neoformans H99
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant protein Cryptococcus neoformans
recombinant protein Cryptococcus gattii VGIII

Subunits

Subunits Comment Organism
? x * 58000, SDS-PAGE Cryptococcus neoformans
? x * 58000, SDS-PAGE Cryptococcus gattii VGIII