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Literature summary for 1.1.1.205 extracted from

  • Bairagya, H.R.; Mukhopadhyay, B.P.; Sekar, K.
    An insight to the dynamics of conserved water molecular triad in IMPDH II (human): recognition of cofactor and substrate to catalytic Arg 322 (2009), J. Biomol. Struct. Dyn., 27, 149-158.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information involvement of three conserved water molecules (W(L), W(M), and W(C)) in the recognition of catalytic residues (R 322, D 364, and N 303) to inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P12268
-
-

Synonyms

Synonyms Comment Organism
IMPDH II
-
Homo sapiens
inosine 5' monophosphate dehydrogenase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
additional information involvement of three conserved water molecules (W(L), W(M), and W(C)) in the recognition of catalytic residues (R 322, D 364, and N 303) to cofactor Homo sapiens