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Literature summary for 1.1.1.205 extracted from

  • Gilbert, H.J.; Drabble, W.T.
    Active-site modification of native and mutant forms of inosine 5-monophosphate dehydrogenase from Escherichia coli K12 (1980), Biochem. J., 191, 533-541.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.205

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoate)
-
 Escherichia coli
6-Chloro-9-beta-D-ribofuranosylpurine 5 '-phosphate covalent modification of the enzyme, total inactivation after 15 min at 0.01 mg/ml Cl-IMP, activity can be restored with 2-mercaptoethanol Escherichia coli
iodoacetamide
-
 Escherichia coli
iodoacetate
-
 Escherichia coli
methyl methanethiosulfonate
-
 Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
inosine 5'-phosphate + NAD+ + H2O
-
 Escherichia coli xanthosine 5'-phosphate + NADH
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Escherichia coli