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Literature summary for 1.1.1.205 extracted from

  • Lambden, P.R.; Drabble, W.T.
    Inosine 5-monophosphate dehydrogenase of Escherichia coli K12: the nature of the inhibition by guanosine 5-monophosphate (1973), Biochem. J., 133, 607-608.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
GMP competitive with respect to IMP and non competitive with respect to NAD+ Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
guaA strain PL 1068
-

Purification (Commentary)

Purification (Comment) Organism
partial purification Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
inosine 5'-phosphate + NAD+ + H2O
-
Escherichia coli xanthosine 5'-phosphate + NADH
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
assay at Escherichia coli

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Escherichia coli