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Literature summary for 1.1.1.201 extracted from
- Bile induction of 7alpha- and 7beta-hydroxysteroid dehydrogenases in Clostridium absonum (1981), Biochim. Biophys. Acta, 665, 262-269.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.009 | - |
3alpha,7beta-dihydroxy-5beta-cholanoic acid | - |
Clostridium sardiniense |  |
| 0.072 | - |
NADP+ | - |
Clostridium sardiniense | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3alpha,7beta-dihydroxy-5beta-cholanoic acid + NADP+ | Clostridium sardiniense | ursodeoxycholic acid | 3alpha-hydroxy-7-oxo-5beta-cholanoic acid + NADPH | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium sardiniense | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | bile salt induction of enzymes synthesis | Clostridium sardiniense | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3alpha,7beta-dihydroxy-5beta-cholanoic acid + NADP+ | ursodeoxycholic acid | Clostridium sardiniense | 3alpha-hydroxy-7-oxo-5beta-cholanoic acid + NADPH | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9.5 | - |
- |
Clostridium sardiniense |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Clostridium sardiniense | |
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