Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Alrestatin | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.004 | - |
n-octadecanal | - |
Rattus norvegicus | |
0.008 | - |
n-hexadecanal | - |
Rattus norvegicus | |
0.014 | - |
n-tetradecanal | - |
Rattus norvegicus | |
0.019 | - |
n-dodecanal | enzyme from brain | Rattus norvegicus | |
0.02 | - |
n-dodecanal | enzyme from liver and kidney | Rattus norvegicus | |
0.07 | - |
n-decanal | - |
Rattus norvegicus | |
0.2 | - |
p-nitrobenzaldehyde | enzyme from kidney, brain or liver | Rattus norvegicus | |
0.77 | - |
n-octanal | - |
Rattus norvegicus | |
1.2 | - |
4-Pyridinecarboxaldehyde | enzyme from kidney, brain or liver | Rattus norvegicus | |
3.3 | - |
propionaldehyde | - |
Rattus norvegicus | |
3.8 | - |
acetaldehyde | - |
Rattus norvegicus | |
24 | - |
ethyl acetoacetate | enzyme from brain or liver | Rattus norvegicus | |
25 | - |
ethyl acetoacetate | enzyme from kidney | Rattus norvegicus | |
42 | - |
D-glucuronate | enzyme from brain | Rattus norvegicus | |
43 | - |
D-glucuronate | enzyme from kidney, or liver | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
cytosol | - |
Bos taurus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
- |
Bos taurus |
32000 | - |
gel filtration | Rattus norvegicus |
37000 | - |
1 * 37000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ethylacetoacetate + NADPH | Rattus norvegicus | - |
ethyl L-(+)-3-hydroxybutyrate + NADP+ | - |
? | |
succinic semialdehyde + NADPH + H+ | Rattus norvegicus | - |
4-hydroxybutyrate + NADP+ | - |
? | |
succinic semialdehyde + NADPH + H+ | Bos taurus | - |
4-hydroxybutyrate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bovine | - |
Cavia porcellus | - |
guinea pig | - |
Rattus norvegicus | - |
rat | - |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Cavia porcellus | - |
brain | - |
Rattus norvegicus | - |
brain | - |
Bos taurus | - |
heart | - |
Cavia porcellus | - |
heart | - |
Rattus norvegicus | - |
heart | muscle | Bos taurus | - |
kidney | - |
Cavia porcellus | - |
kidney | - |
Rattus norvegicus | - |
kidney | - |
Bos taurus | - |
liver | - |
Cavia porcellus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
5.9 | - |
liver enzyme | Rattus norvegicus |
6 | - |
brain enzyme | Rattus norvegicus |
11.02 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-pyridinecarboxaldehyde + NADPH | - |
Rattus norvegicus | 4-pyridinemethanol + NADP+ | - |
r | |
acetaldehyde + NADPH + H+ | - |
Rattus norvegicus | ethanol + NADP+ | - |
? | |
daunorubicin + NADPH | - |
Rattus norvegicus | ? + NADP+ | - |
? | |
ethylacetoacetate + NADPH | - |
Rattus norvegicus | ethyl L-(+)-3-hydroxybutyrate + NADP+ | - |
? | |
n-decanal + NADPH + H+ | - |
Rattus norvegicus | n-decanol + NADP+ | - |
r | |
n-dodecanal + NADPH + H+ | - |
Rattus norvegicus | n-dodecanol + NADP+ | - |
r | |
n-hexadecanal + NADPH + H+ | - |
Rattus norvegicus | n-hexadecanol + NADP+ | - |
r | |
n-octadecanal + NADPH + H+ | - |
Rattus norvegicus | n-octadecanol + NADP+ | - |
r | |
n-octanal + NADPH + H+ | - |
Rattus norvegicus | n-octanol + NADP+ | - |
r | |
n-tetradecanal + NADPH + H+ | - |
Rattus norvegicus | n-tetradecanol + NADP+ | - |
r | |
p-nitrobenzaldehyde + NADPH | - |
Rattus norvegicus | p-nitrobenzylalcohol + NADP+ | - |
r | |
p-nitrobenzaldehyde + NADPH | - |
Bos taurus | p-nitrobenzylalcohol + NADP+ | - |
r | |
propionaldehyde + NADPH | - |
Rattus norvegicus | propanol + NADP+ | - |
r | |
succinic semialdehyde + NADPH + H+ | - |
Rattus norvegicus | 4-hydroxybutyrate + NADP+ | - |
? | |
succinic semialdehyde + NADPH + H+ | - |
Rattus norvegicus | 4-hydroxybutyrate + NADP+ | - |
r | |
succinic semialdehyde + NADPH + H+ | - |
Bos taurus | 4-hydroxybutyrate + NADP+ | - |
? | |
succinic semialdehyde + NADPH + H+ | - |
Bos taurus | 4-hydroxybutyrate + NADP+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Bos taurus |
monomer | 1 * 37000, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
for reduction of p-pyridinecarboxaldehyde | Rattus norvegicus |