Application | Comment | Organism |
---|---|---|
additional information | CAD is a useful tool to improve lignin digestibility and/or to lower the lignin levels in plants. Enzyme knockout modification targeted directly to block lignin synthesis causes not only reduced lignin level in fibre, but also affects amount and organization of cellulose and pectin. The process of retting in the transgenic straw is more uniform, which might contribute to an improvement in the fibre quality. Such plants can be successfully cultivated in a field | Linum usitatissimum |
Cloned (Comment) | Organism |
---|---|
gene CAD, phylogenetic analysis and tree | Linum usitatissimum |
Protein Variants | Comment | Organism |
---|---|---|
additional information | CAD down-regulation does not lead to the accumulation of lignin precursors, evaluated composition and properties of flax fibre from plants with silenced CAD gene. CAD downregulation does not disturb at all or has only slight effect on flax plants' development in vivo, while the resistance against flax major pathogen Fusarium oxysporum decreases slightly. The modification positively affects fibre possessing, it results in more uniform retting. Even if the overall retting time is not shortened, CAD straw is colonized by microorganisms much quicker, and the pectin degradation enzymes act effectively from the very beginning of the retting. The process of retting in the transgenic straw is more uniform, which might contribute to an improvement in the fibre quality | Linum usitatissimum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell wall | - |
Linum usitatissimum | 5618 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cinnamyl alcohol + NADP+ | Linum usitatissimum | - |
cinnamaldehyde + NADPH + H+ | - |
r | |
cinnamyl alcohol + NADP+ | Linum usitatissimum Nike | - |
cinnamaldehyde + NADPH + H+ | - |
r | |
coniferyl alcohol + NADP+ | Linum usitatissimum | - |
coniferyl aldehyde + NADPH + H+ | - |
r | |
coniferyl alcohol + NADP+ | Linum usitatissimum Nike | - |
coniferyl aldehyde + NADPH + H+ | - |
r | |
p-coumaryl alcohol + NADP+ | Linum usitatissimum | - |
p-coumaryl aldehyde + NADPH + H+ | - |
r | |
p-coumaryl alcohol + NADP+ | Linum usitatissimum Nike | - |
p-coumaryl aldehyde + NADPH + H+ | - |
r | |
sinapyl alcohol + NADP+ | Linum usitatissimum | - |
sinapyl aldehyde + NADPH + H+ | - |
r | |
sinapyl alcohol + NADP+ | Linum usitatissimum Nike | - |
sinapyl aldehyde + NADPH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Linum usitatissimum | Q1HGA8 | - |
- |
Linum usitatissimum Nike | Q1HGA8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
stem | - |
Linum usitatissimum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cinnamyl alcohol + NADP+ | - |
Linum usitatissimum | cinnamaldehyde + NADPH + H+ | - |
r | |
cinnamyl alcohol + NADP+ | - |
Linum usitatissimum Nike | cinnamaldehyde + NADPH + H+ | - |
r | |
coniferyl alcohol + NADP+ | - |
Linum usitatissimum | coniferyl aldehyde + NADPH + H+ | - |
r | |
coniferyl alcohol + NADP+ | - |
Linum usitatissimum Nike | coniferyl aldehyde + NADPH + H+ | - |
r | |
p-coumaryl alcohol + NADP+ | - |
Linum usitatissimum | p-coumaryl aldehyde + NADPH + H+ | - |
r | |
p-coumaryl alcohol + NADP+ | - |
Linum usitatissimum Nike | p-coumaryl aldehyde + NADPH + H+ | - |
r | |
sinapyl alcohol + NADP+ | - |
Linum usitatissimum | sinapyl aldehyde + NADPH + H+ | - |
r | |
sinapyl alcohol + NADP+ | - |
Linum usitatissimum Nike | sinapyl aldehyde + NADPH + H+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
CAD | - |
Linum usitatissimum |
cinnamyl alcohol dehydrogenase | - |
Linum usitatissimum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Linum usitatissimum | |
NADPH | - |
Linum usitatissimum |
General Information | Comment | Organism |
---|---|---|
evolution | flax CAD belongs to the bona-fide CAD family, phylogenetic analysis | Linum usitatissimum |
malfunction | CAD downregulation does not disturb at all or has only slight effect on flax plants' development in vivo, while the resistance against flax major pathogen Fusarium oxysporum decreases slightly. The modification positively affects fibre possessing, it results in more uniform retting | Linum usitatissimum |
metabolism | cinnamyl alcohol dehydrogenase is a key enzyme in the lignin biosynthesis, lignin biosynthesis pathway within the phenylpropanoid route, overview | Linum usitatissimum |