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Literature summary for 1.1.1.186 extracted from

  • Katan, R.; Avigad, G.
    NADP dependent oxidation of TDP-glucose by an enzyme system from sugar beets (1966), Biochem. Biophys. Res. Commun., 24, 18-24.
    View publication on PubMed
Search for more literature for 1.1.1.186

General Stability

General Stability Organism
freezing and thawing inactivate, incubation with 1 mM TDP-D-glucose stabilizes 2-3fold Beta vulgaris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
TDP-D-glucose + 2 NADP+ + H2O Beta vulgaris epimerization of TDP-D-glucose to TDP-D-galactose TDP-D-galacturonate + 2 NADPH + 2 H+
-
 ?

Organism

Organism UniProt Comment Textmining
Beta vulgaris
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial, contains TDP-D-glucose 4-epimerase Beta vulgaris

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Beta vulgaris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
TDP-D-glucose + 2 NADP+ + H2O epimerization of TDP-D-glucose to TDP-D-galactose Beta vulgaris TDP-D-galacturonate + 2 NADPH + 2 H+
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4
-
 half-life: 10 h Beta vulgaris

Cofactor

Cofactor Comment Organism Structure
NADP+ cannot be replaced by NAD+ Beta vulgaris