Protein Variants | Comment | Organism |
---|---|---|
A89N/F154Y | Vmax and kcat values of the mutant enzyme are enhanced by 2.08 and 3.86fold, respectively, while the Km value decreases by 2.36fold compared to the wild type enzyme | Rhodotorula toruloides |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N,N-dimethyl-3-keto-3-(2-thienyl)-1-keto propanamine + NADPH + H+ | Rhodotorula toruloides | mutant enzyme A89N/F154Y with yield of 91.2% and S-enantiomeric excess of 99.9% | (S)-3-(dimethylamino)-1-(2-thienyl)-1-propanol + NADP+ | - |
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Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodotorula toruloides | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N,N-dimethyl-3-keto-3-(2-thienyl)-1-keto propanamine + NADPH + H+ | mutant enzyme A89N/F154Y with yield of 91.2% and S-enantiomeric excess of 99.9% | Rhodotorula toruloides | (S)-3-(dimethylamino)-1-(2-thienyl)-1-propanol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCR9 | - |
Rhodotorula toruloides |