Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.18 extracted from

  • Berman, T.; Magasanik, B.
    The pathway of myo-inositol degradation in Aerobacter aerogenes. Dehydrogenation and dehydration (1966), J. Biol. Chem., 241, 800-806.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-keto-myo-inositol
-
Klebsiella aerogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-2,3-diketo-4-deoxy-epi-inositol + NADH Klebsiella aerogenes
-
ketodeoxyinositol + NAD+
-
?
myo-inositol + NAD+ Klebsiella aerogenes
-
2,4,6/3,5-pentahydroxycyclohexanone + NADH
-
?

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Klebsiella aerogenes

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Klebsiella aerogenes
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
280
-
-
Klebsiella aerogenes

Storage Stability

Storage Stability Organism
-10°C, several months Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-2,3-diketo-4-deoxy-epi-inositol + NADH
-
Klebsiella aerogenes ketodeoxyinositol + NAD+
-
?
myo-inositol + NAD+
-
Klebsiella aerogenes 2,4,6/3,5-pentahydroxycyclohexanone + NADH
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+ preferred hydrogen acceptor Klebsiella aerogenes
NADH
-
Klebsiella aerogenes