Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | ligand bindig modelling for inhibitor design | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ketopantoate + NADPH | Escherichia coli | the enzyme is involved in pantothenate, i.e. vitamin B5, biosynthesis, which is a precursor for CoA | pantoate + NADP+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
gene panE | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ketopantoate + NADPH | the enzyme is involved in pantothenate, i.e. vitamin B5, biosynthesis, which is a precursor for CoA | Escherichia coli | pantoate + NADP+ | - |
r | |
ketopantoate + NADPH | the 4-proS hydrogen is transferred from NADPH to ketopantoate to form pantoate and NADP+, ligand binding analysis by NMR spectroscopy | Escherichia coli | pantoate + NADP+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
ketopantoate reductase | - |
Escherichia coli |
KPR | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | cofactor binding structure and thermodynamics | Escherichia coli | |
NADPH | cofactor binding structure and thermodynamics | Escherichia coli |