Crystallization (Comment) | Organism |
---|---|
- |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0262 | - |
17alpha-hydroxyprogesterone | isozyme HSD-I | Sus scrofa | |
0.118 | - |
17alpha-hydroxyprogesterone | isozyme HSD-II | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
isozyme HSD-I, HSD-II, gel filtration | Sus scrofa |
39000 | - |
isozyme HSD-I, SDS-PAGE | Sus scrofa |
40000 | - |
isozyme HSD-II, SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | both isozymes | Sus scrofa |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation, affinity chromatography | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxyprogesterone + NAD(P)H + H+ | NADPH preferred | Sus scrofa | 17alpha,20alpha-dihydroxy-pregn-4-en-3-one + NAD(P)+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 39000 isozyme HSD-I, 1 * 40000 isozyme HSD-I, SDS-PAGE | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Sus scrofa | |
NADPH | preferred | Sus scrofa |