Literature summary for 1.1.1.146 extracted from

Abbott, A.N.; Guidry, T.V.; Welsh, K.J.; Thomas, A.M.; Kling, M.A.; Hunter, R.L.; Actor, J.K.
11beta-hydroxysteroid dehydrogenases are regulated during the pulmonary granulomatous response to the mycobacterial glycolipid trehalose-6,6-dimycolate (2009), Neuroimmunomodulation, 16, 147-154.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	11beta-HSD2mRNA expression increases 2.5fold on day 3 after injection of trehalose-6,6'-dimycolate	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	11beta-HSD1 mRNA decreases 4fold on day 3 after injection of trehalose-6,6'-dimycolate	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lung	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
11beta-HSD1	isozyme	Mus musculus
11beta-HSD2	isozyme	Mus musculus

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Release 2023.1 (January 2023)