Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NADP+ | Homo sapiens | i.e. cortisol | 17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADPH | i.e. cortisol | r | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | Homo sapiens | i.e. cortisone | 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | two forms present, one NAD-specific the other NADP+-dependent | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NADP+ | i.e. cortisol | Homo sapiens | 17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADPH | i.e. cortisol | r | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | i.e. cortisone | Homo sapiens | 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |