Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | MtDH transcript increases after treatment with tobacco leaf extract | Alternaria alternata | |
additional information | transcript of both MtDH and MPDH start to increase by 30 min after the addition of tobacco extract, reaching 2.5fold to almost 4fold higher by 2 h. No increase in transcript for MtDH and MPDH if cultures are treated with water instead of tobacco leaf extract | Alternaria alternata |
Protein Variants | Comment | Organism |
---|---|---|
additional information | MtDH mutant produces less mannitol than compared to the wild-type. The MtDH/MPDH double mutant does not produce mannitol. Response of the genes in the disruption mutants is similar to that in wild-type. Conidia of mutants are viable and germinated normally. Elevated levels of trehalose in the mutants, suggesting that trehalose may substitute for mannitol as a storage compound for germination. Tobacco inoculation shows no reduction in lesion severity caused by the MtDH mutant as compared with wild-type, whereas the MtDH/MPDH double mutant causes significantly less disease. The double mutant is unaffected in the ability to germinate and produce appressoria on tobacco leaves and elicites a defense response from the host, indicating that it is able to penetrate and infect the host | Alternaria alternata |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Alternaria alternata | - |
- |
- |
Alternaria alternata A5 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-mannitol + NAD(P)+ | - |
Alternaria alternata | D-fructose + NAD(P)H + H+ | - |
? | |
D-mannitol + NAD(P)+ | - |
Alternaria alternata A5 | D-fructose + NAD(P)H + H+ | - |
? | |
D-mannitol + NADP+ | - |
Alternaria alternata | D-fructose + NADPH + H+ | - |
r | |
D-mannitol + NADP+ | - |
Alternaria alternata A5 | D-fructose + NADPH + H+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
MtDH | - |
Alternaria alternata |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Alternaria alternata |