Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.107 extracted from

  • Chu, H.N.; Kobayashi, J.; Mikami, B.; Yagi, T.
    The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti (2011), Biosci. Biotechnol. Biochem., 75, 388-390.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli strain BL21(DE3) Mesorhizobium loti

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyridoxal + NAD+ Mesorhizobium loti
-
4-pyridoxolactone + NADH + H+
-
ir

Organism

Organism UniProt Comment Textmining
Mesorhizobium loti
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyridoxal + NAD+
-
Mesorhizobium loti 4-pyridoxolactone + NADH + H+
-
ir
pyridoxal + NAD+ via pyridoxal hemiacetal Mesorhizobium loti 4-pyridoxolactone + NADH + H+
-
ir

Synonyms

Synonyms Comment Organism
PLDH
-
Mesorhizobium loti

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Mesorhizobium loti

General Information

General Information Comment Organism
evolution the enzyme belongs to the short-chain dehydrogenase/reductase enzyme family Mesorhizobium loti
additional information structure analysis, homology modeling using the crystal structure of (S)-1-phenylethanol dehydrogenase, PDB ID 2EW8, molecular replacement, overview Mesorhizobium loti
physiological function the enzyme is involved in the degradation pathway I of pyridoxine, a vitamin B6 compound Mesorhizobium loti