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Literature summary for 1.1.1.1 extracted from

  • Orywal, K.; Jelski, W.; Zdrodowski, M.; Szmitkowski, M.
    The activity of class I, II, III and IV alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in cervical cancer (2011), Clin. Biochem., 44, 1231-1234.
    View publication on PubMed
Search for more literature for 1.1.1.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-butanol + NAD+ Homo sapiens
-
 butanal + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adenocarcinoma cell
-
 Homo sapiens
-
cervical cancer cell
-
 Homo sapiens
-
additional information activity of ADH isoenzymes and ALDH in cervical carcinoma and healthy tissues., overview Homo sapiens
-
uterus
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-butanol + NAD+
-
 Homo sapiens butanal + NADH + H+
-
 ?
3-nitrobenzaldehyde + NADH + H+ class IV isozyme, reductive activity Homo sapiens 3-nitrobenzyl alcohol + NAD+
-
 ?
4-methoxy-1-naphthaldehyde + NAD+ fluorogenic substrate of class I and II isozymes Homo sapiens 4-methoxy-1-naphthol + NADH + H+
-
 ?
4-nitrosodimethylaniline + NAD+ photometric assay substrate Homo sapiens ? + NADH + H+
-
 ?
6-methoxy-2-naphthaldehyde + NADH + H+ class II isozyme, reductive activity Homo sapiens (6-methoxynaphthalen-2-yl)methanol + NAD+
-
 ?

Synonyms

Synonyms Comment Organism
ADH
-
 Homo sapiens
aldehyde dehydrogenase
-
 Homo sapiens
ALDH
-
 Homo sapiens
class I ADH
-
 Homo sapiens
class II ADH
-
 Homo sapiens
class III ADH
-
 Homo sapiens
class IV ADH
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at, class IV enzyme, reduction reaction Homo sapiens
7.6
-
 assay at, class II enzyme, reduction reaction Homo sapiens
8
-
 assay at, class III enzyme, reduction reaction Homo sapiens
8.5
-
 assay at, total ADH activity Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens