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BRENDA support

Ligand 2,3-Diaminopropionate

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Basic Ligand Information

Molecular Structure
Picture of 2,3-Diaminopropionate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C3H8N2O2
2,3-Diaminopropionate
PECYZEOJVXMISF-UHFFFAOYSA-M
Synonyms:
(R,S)-2,3-diaminopropionic acid, 2,3-Diaminopropanoate, 2,3-Diaminopropionic acid, alpha,beta-Alanine, alpha,beta-diaminopropionate, alpha,beta-diaminopropionic acid, DL-2,3-diaminopropanoate, DL-2,3-diaminopropionate, DL-2,3-Diaminopropionic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-diaminopropanoate + H2O = pyruvate + 2 NH3
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R,S)-2,3-Diaminopropionic acid + pyruvate + NADH = ?
show the reaction diagram
-
alpha,beta-diaminopropionic acid = ?
show the reaction diagram
-
alpha,beta-diaminopropionate = ?
show the reaction diagram
-
ATP + L-His + 2,3-diaminopropanoate = AMP + phosphate + 2,3-diaminopropanoyl-L-His
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-carbamoyl-alpha-amino-beta-alanine + H2O = 2,3-diaminopropanoate + CO2 + NH3
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates, but remains unchanged
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
noncompetitive inhibition with respect to delta-aminovalerate, competitive inhibition to 2-oxoglutarate
-
slight
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (12 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
11.9
-
pyruvate and NADH as cosubstrates
0.6
-
strain B/1t7-A

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.035
-
25°C, pH 7.8

References & Links

Links to other databases for 2,3-Diaminopropionate

EXTERNAL LINKS