Ligand farnesyl phosphate

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Basic Ligand Information

Molecular Structure
Picture of farnesyl phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H27O4P
farnesyl phosphate
ALEWCKXBHSDCCT-YFVJMOTDSA-L
Synonyms:
(2E,6E)-farnesyl phosphate, farnesyl monophosphate, phosphoryl-polyprenol, trans,trans-farnesyl phosphate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDP-alpha-D-mannose + farnesyl phosphate = GDP + farnesyl beta-D-mannosyl phosphate
show the reaction diagram
-
farnesyl phosphate + isopentenyl diphosphate = phosphate + di-trans-poly-cis-undecaprenyl diphosphate
show the reaction diagram
-
farnesyl monophosphate + Gly-Cys-Val-Leu-Ser = phosphate + Gly-S-farnesyl-Cys-Val-Leu-Ser
show the reaction diagram
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ATP + (2E,6E)-farnesyl phosphate = ADP + (2E,6E)-farnesyl diphosphate
show the reaction diagram
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CTP + (2E,6E)-farnesyl phosphate = CDP + (2E,6E)-farnesyl diphosphate
show the reaction diagram
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farnesyl phosphate + H2O = farnesol + phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + (2E,6E)-farnesol = ADP + (2E,6E)-farnesyl phosphate
show the reaction diagram
-
-
farnesyl diphosphate + H2O = farnesyl phosphate + phosphate
show the reaction diagram
-
-
farnesyl diphosphate + H2O = farnesyl phosphate + phosphate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
hydrolysis of solanesyl phosphate
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.71
-
recombinant enzyme

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.07
-
pH 5.5, 37°C

References & Links

Links to other databases for farnesyl phosphate

ChEBI
PubChem
ChEBI
PubChem