Ligand tryptophol

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Basic Ligand Information

Molecular Structure
Picture of tryptophol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H11NO
tryptophol
MBBOMCVGYCRMEA-UHFFFAOYSA-N
Synonyms:
(indol-3-yl)ethanol, 1-(1H-indol-3-yl)ethanol, 2-(1H-indol-3-yl)ethanol, 3-indoleethanol, 3-indolethanol, indol-3-ethanol, indole-3-ethanol


Show all pahtways known for Show all BRENDA pathways known for tryptophol

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
indole-3-acetaldehyde + NADH = indole-3-ethanol + NAD+
show the reaction diagram
-
indole-3-acetaldehyde + NADPH = indole-3-ethanol + NADP+
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tryptophol + NAD+ = ? + NADH
show the reaction diagram
-
3-indolethanol + O2 = ?
show the reaction diagram
-
acetyl-CoA + tryptophol = CoA + N-acetyltryptophol
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
indole-3-acetaldehyde + NADH = indole-3-ethanol + NAD+
show the reaction diagram
-
indole-3-acetaldehyde + NADPH = indole-3-ethanol + NADP+
show the reaction diagram
-
indol-3-ylacetaldehyde + NADPH = indol-3-ethanol + NADP+
show the reaction diagram
-
-
indole-3-acetaldehyde + NAD(P)H = indole-3-ethanol + NAD(P)+
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activation up to 0.1 mM
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
dead end inhibitor analog, competitive versus tryptamine
-

3D Structure of Enzyme-Ligand-Complex (PDB) (8 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.83
-
-

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2
-
0.1 M glycine-NaOH buffer, pH 10.0, 25°C

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for tryptophol

ChEBI
PubChem
ChEBI
PubChem