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Ligand taurine

Basic Ligand Information

Molecular Structure

Related pathways

Pathway Source

Pathways

BRENDA

bile acid biosynthesis, neutral pathway, cysteine metabolism, taurine degradation

KEGG

ABC transporters, Neuroactive ligand-receptor interaction, Primary bile acid biosynthesis, Sulfur metabolism, Taurine and hypotaurine metabolism

MetaCyc

bile acid biosynthesis, neutral pathway, bile acids deconjugation, pyruvate fermentation to opines, taurine biosynthesis I, taurine biosynthesis II, taurine biosynthesis III, taurine degradation I, taurine degradation II, taurine degradation III, taurine degradation IV, tRNA-uridine 2-thiolation (mammalian mitochondria) more

Show all BRENDA pathways known for taurine

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (17 results)

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Show Natural Substrate (17 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.2.2

Cl- + H2O2 + H+ + taurine + H+ = taurine monochloroamine + 2 H2O

712338

-

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

657933, 657996, 658975, 658984, 658130, 712249, 725787, 723940, 724974, 764167, 764499, 764972, 765270

1GQW, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

657933, 657996, 658975, 658984, 658130, 712249, 725787, 723940, 724974, 764167, 764499, 764972, 765270

1GY9, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

657933, 657996, 658975, 658984, 658130, 712249, 725787, 723940, 724974, 764167, 764499, 764972, 765270

1OS7, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

657933, 657996, 658975, 658984, 658130, 712249, 725787, 723940, 724974, 764167, 764499, 764972, 765270

1OTJ, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

657933, 657996, 658975, 658984, 658130, 712249, 725787, 723940, 724974, 764167, 764499, 764972, 765270

6EDH, 3D-view

1.4.99.2

taurine + H2O + acceptor = sulfoacetaldehyde + NH3 + reduced acceptor

395284, 395285

-

1.4.99.2

taurine + H2O + bovine heart cytochrome c = 2-sulfoacetaldehyde + NH3 + reduced bovine heart cytochrome c

720393

-

1.4.99.2

taurine + H2O + cytochrome c = sulfoacetaldehyde + NH3 + reduced cytochrome c

656739

-

1.4.99.2

taurine + H2O + ferricyanide = 2-sulfoacetaldehyde + NH3 + ferrocyanide

720393

-

1.14.11.17

5 entries

1.4.99.2

4 entries

1.5.1.23

taurine + NADH + H+ + pyruvate = tauropine + NAD+ + H2O

688792

-

2.3.1.65

choloyl-CoA + taurine = CoA + taurocholate

487364, 487366, 487372, 487367, 487365, 487369, 487368, 487371, 487373, 757369

-

2.6.1.55

taurine + 2-oxoglutarate = 2-sulfoacetaldehyde + L-glutamate

758762

-

2.6.1.77

taurine + pyruvate = 2-sulfoacetaldehyde + L-alanine

695918

-

2.6.1.77

taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde

640198, 640199, 640197, 662781, 662780

-

2.6.1.77

taurine + pyruvate = sulfoacetaldehyde + L-alanine

671638

-

2.6.1.77

3 entries

7.6.2.7

ATP + H2O + taurine/out = ADP + phosphate + taurine/in

210348

-

In Vivo Product in Enzyme-catalyzed Reactions (64 results)

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Show Natural Product (64 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.13.8

hypotaurine + H2O + NAD+ = taurine + NADH

394698

-

1.14.13.8

hypotaurine + NADH + H+ + O2 = taurine + NAD+ + H2O

-

-

1.14.13.8

hypotaurine + NADPH + H+ + O2 = taurine + NADP+ + H2O

-

-

1.5.1.23

tauropine + NAD+ + H2O = taurine + pyruvate + NADH

-

-

1.5.1.23

tauropine + NAD+ + H2O = taurine + pyruvate + NADH + H+

-

-

3.5.1.24

taurocholic acid + H2O = taurin + cholic acid

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurin + cholic acid

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurin + cholic acid

-

7SVG, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = beta-muricholate + taurine

-

2BJF, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = beta-muricholate + taurine

-

7SVF, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = beta-muricholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = taurine + chenodeoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = taurine + chenodeoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = taurine + chenodeoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholate

-

2BJF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholate

-

7SVF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholate

-

7SVG, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholic acid

-

2BJF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholic acid

-

7SVF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholic acid

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = cholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = cholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = cholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholate

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholate

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholate

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholic acid

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholic acid

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholic acid

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholate

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholate

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholate

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = deoxycholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = deoxycholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = deoxycholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurolithocholic acid + H2O = lithocholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = lithocholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = lithocholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurolithocholic acid + H2O = taurine + lithocholic acid

-

2BJF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = taurine + lithocholic acid

-

7SVF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = taurine + lithocholic acid

-

7SVG, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

2BJF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

7SVF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

7SVG, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = ursodeoxycholate + taurine

-

2BJF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = ursodeoxycholate + taurine

-

7SVF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = ursodeoxycholate + taurine

-

7SVG, 3D-view

1.14.13.8

3 entries

1.5.1.23

2 entries

3.5.1.24

57 entries

4.1.1.122

L-cysteate = taurine + CO2

-

-

7.6.2.7

ATP + H2O + taurine/out = ADP + phosphate + taurine/in

-

-

Substrate in Enzyme-catalyzed Reactions (78 results)

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Show Substrate (78 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.1.18

taurine + Br- + peracetic acid = bromotaurine + ?

671956

-

1.11.1.7

taurine + Cl- + H2O2 = taurine chloramine + HOCl + H2O

712714

-

1.11.2.2

Cl- + H2O2 + H+ + taurine + H+ = taurine monochloroamine + 2 H2O

712338, 742440, 742569

-

1.11.2.2

taurine + Cl- + H2O2 = taurine chloramine + H2O

724229, 725677

-

1.14.11.17

O2 + 2-oxoglutarate + taurine = ?

698476

1GQW, 3D-view

1.14.11.17

O2 + 2-oxoglutarate + taurine = ?

698476

1GY9, 3D-view

1.14.11.17

O2 + 2-oxoglutarate + taurine = ?

698476

1OS7, 3D-view

1.14.11.17

O2 + 2-oxoglutarate + taurine = ?

698476

1OTJ, 3D-view

1.14.11.17

O2 + 2-oxoglutarate + taurine = ?

698476

6EDH, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = CO2 + succinate + sulfite + aminoacetaldehyde

701264

1GQW, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = CO2 + succinate + sulfite + aminoacetaldehyde

701264

1GY9, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = CO2 + succinate + sulfite + aminoacetaldehyde

701264

1OS7, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = CO2 + succinate + sulfite + aminoacetaldehyde

701264

1OTJ, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = CO2 + succinate + sulfite + aminoacetaldehyde

701264

6EDH, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = succinate + CO2 + 2-aminoethanal + sulfite

697475

1GQW, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = succinate + CO2 + 2-aminoethanal + sulfite

697475

1GY9, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = succinate + CO2 + 2-aminoethanal + sulfite

697475

1OS7, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = succinate + CO2 + 2-aminoethanal + sulfite

697475

1OTJ, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = succinate + CO2 + 2-aminoethanal + sulfite

697475

6EDH, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

285263, 657933, 657996, 658975, 658984, 658130, 671301, 671717, 674930, 673044, 673443, 688192, 712249, 725787, 723940, 724974, 742651, 764167, 764499, 764972, 765270

1GQW, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

285263, 657933, 657996, 658975, 658984, 658130, 671301, 671717, 674930, 673044, 673443, 688192, 712249, 725787, 723940, 724974, 742651, 764167, 764499, 764972, 765270

1GY9, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

285263, 657933, 657996, 658975, 658984, 658130, 671301, 671717, 674930, 673044, 673443, 688192, 712249, 725787, 723940, 724974, 742651, 764167, 764499, 764972, 765270

1OS7, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

285263, 657933, 657996, 658975, 658984, 658130, 671301, 671717, 674930, 673044, 673443, 688192, 712249, 725787, 723940, 724974, 742651, 764167, 764499, 764972, 765270

1OTJ, 3D-view

1.14.11.17

taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

285263, 657933, 657996, 658975, 658984, 658130, 671301, 671717, 674930, 673044, 673443, 688192, 712249, 725787, 723940, 724974, 742651, 764167, 764499, 764972, 765270

6EDH, 3D-view

1.14.11.17

taurine + alpha-ketoadipate + O2 = sulfite + aminoacetaldehyde + pentan-1,5-dioic acid + CO2

285263

1GQW, 3D-view

1.14.11.17

taurine + alpha-ketoadipate + O2 = sulfite + aminoacetaldehyde + pentan-1,5-dioic acid + CO2

285263

1GY9, 3D-view

1.14.11.17

taurine + alpha-ketoadipate + O2 = sulfite + aminoacetaldehyde + pentan-1,5-dioic acid + CO2

285263

1OS7, 3D-view

1.14.11.17

taurine + alpha-ketoadipate + O2 = sulfite + aminoacetaldehyde + pentan-1,5-dioic acid + CO2

285263

1OTJ, 3D-view

1.14.11.17

taurine + alpha-ketoadipate + O2 = sulfite + aminoacetaldehyde + pentan-1,5-dioic acid + CO2

285263

6EDH, 3D-view

1.4.99.2

taurine + H2O + 2,6-dichlorophenol indophenol = sulfoacetaldehyde + NH3 + reduced 2,6-dichlorophenol indophenol

656739

-

1.4.99.2

taurine + H2O + acceptor = sulfoacetaldehyde + NH3 + reduced acceptor

395284, 395285, 671648, 675824

-

1.4.99.2

taurine + H2O + bovine heart cytochrome c = 2-sulfoacetaldehyde + NH3 + reduced bovine heart cytochrome c

720393

-

1.4.99.2

taurine + H2O + cytochrome c = sulfoacetaldehyde + NH3 + reduced cytochrome c

656739

-

1.4.99.2

taurine + H2O + ferricyanide = 2-sulfoacetaldehyde + NH3 + ferrocyanide

720393

-

1.4.99.2

taurine + H2O + phenazine methosulfate = sulfoacetaldehyde + NH3 + reduced phenazine methosulfate

395284, 395285

-

1.5.1.23

Taurine + 2-oxobutanoate + NADH = ?

13435, 13440, 13439, 13437

-

1.5.1.23

Taurine + 2-oxohexanoate + NADH = ?

13440

-

1.5.1.23

Taurine + 2-oxopentanoate + NADH = ?

13435, 13440, 13437, 13436

-

1.5.1.23

Taurine + 3-hydroxypyruvate + NADH = ?

13440, 13437

-

1.5.1.23

Taurine + glyoxylate + NADH = ?

13437, 13439, 13440

-

1.5.1.23

taurine + NADH + H+ + pyruvate = tauropine + NAD+ + H2O

688792

-

1.5.1.23

taurine + oxaloacetate + NADH = ?

13440, 13439, 13437

-

1.5.1.23

Taurine + pyruvate + NADH = Tauropine + NAD+ + H2O

13292, 13300, 13439, 13434, 13440, 13436, 13437, 13435, 13438, 688792

-

1.11.2.2

2 entries

1.14.11.17

25 entries

1.4.99.2

6 entries

1.5.1.23

8 entries

1.97.1.13

taurine + H2O + oxidized benzyl viologen = ?

772986

-

2.1.4.1

arginine + taurine = 2-guanidinoethanesulfonic acid + ornithine

485972

-

2.3.1.280

acetyl-CoA + 2-aminoethanesulfonic acid = CoA + ?

749881

-

2.3.1.65

arachidonoyl-CoA + taurine = CoA + arachidonoyl-taurine

778241

-

2.3.1.65

chenodeoxycholoyl-CoA + taurine = CoA + taurochenodeoxycholate

487368, 487367, 659246

-

2.3.1.65

choloyl-CoA + taurine = CoA + taurocholate

487364, 487365, 487368, 487367, 487372, 487366, 487373, 487369, 487371, 659246, 659664, 675804, 757369

-

2.3.1.65

deoxycholoyl-CoA + taurine = CoA + taurodeoxycholate

487368, 487367

-

2.3.1.65

docosahexaenoyl-CoA + taurine = CoA + docosahexaenoyl-taurine

778241

-

2.3.1.65

lithocholoyl-CoA + taurine = CoA + taurolithocholate

487368, 487367

-

2.3.1.65

oleoyl-CoA + taurine = CoA + oleoyl-taurine

778241

-

2.3.1.65

oleoyl-CoA + taurine = CoA +oleoyl-taurine

778241

-

2.3.1.65

ursodeoxycholoyl-CoA + taurine = CoA + tauroursodeoxycholate

487367

-

2.3.2.2

5-L-glutamyl-4-nitroanilide + taurine = 4-nitroaniline + 5-L-glutamyl-taurine

658567

-

2.3.2.2

D-Gln + taurine = D-Glu-taurine + NH3

657592

-

2.3.2.2

L-Gln + taurine = gamma-glutamyltaurine + NH3

657592

-

2.3.1.65

9 entries

2.3.2.2

3 entries

2.6.1.120

taurine + 2-oxoglutarate = ? + L-glutamate

763227, 763265

-

2.6.1.18

pyruvate + taurine = L-alanine + 2-oxoethanesulfonic acid

288059

-

2.6.1.55

taurine + 2-oxoglutarate = 2-sulfoacetaldehyde + L-glutamate

758762

-

2.6.1.55

taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate

636680, 636678, 636677, 636679

-

2.6.1.77

taurine + 2-oxobutanoate = 2-sulfoacetaldehyde + 2-aminobutanoate

738522

-

2.6.1.77

taurine + 2-oxobutyrate = 2-sulfoacetaldehyde + 2-aminobutyrate

640197

-

2.6.1.77

taurine + 2-oxoglutarate = 2-sulfoacetaldehyde + L-glutamate

662781

-

2.6.1.77

taurine + butanal = 2-sulfoacetaldehyde + butyl-1-amine

737516

-

2.6.1.77

taurine + ethanal = 2-sulfoacetaldehyde + ethylamine

737516

-

2.6.1.77

taurine + glycolaldehyde = 2-sulfoacetaldehyde + ?

737516

-

2.6.1.77

taurine + glyoxylate = 2-sulfoacetaldehyde + glycine

737516

-

2.6.1.77

taurine + hexanal = 2-sulfoacetaldehyde + hexyl-1-amine

737516

-

2.6.1.77

taurine + methanal = 2-sulfoacetaldehyde + methylamine

737516

-

2.6.1.77

taurine + oxaloacetate = ?

640197

-

2.6.1.77

taurine + pentanal = 2-sulfoacetaldehyde + pentylamine

737516

-

2.6.1.77

taurine + propanal = 2-sulfoacetaldehyde + propyl-1-amine

737516

-

2.6.1.77

taurine + pyruvate = 2-sulfoacetaldehyde + L-alanine

640198, 640199, 640200, 640197, 695918, 737516

-

2.6.1.77

taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde

640198, 640199, 640197, 662781, 662780

-

2.6.1.77

taurine + pyruvate = sulfoacetaldehyde + L-alanine

664237, 671638

-

2.6.1.55

2 entries

2.6.1.77

15 entries

7.6.2.7

ATP + H2O + taurine/out = ADP + phosphate + taurine/in

210349, 210348, 210350

-

Product in Enzyme-catalyzed Reactions (139 results)

top print hide

Show Product (139 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.13.8

hypotaurine + H2O + NAD+ = taurine + NADH

394698

-

1.14.13.8

hypotaurine + NADH + H+ + O2 = taurine + NAD+ + H2O

-

-

1.14.13.8

hypotaurine + NADPH + H+ + O2 = taurine + NADP+ + H2O

-

-

1.14.13.8

hypotaurine + O2 + NADH + H+ = taurine + NAD+ + H2O

-

-

1.14.13.8

hypotaurine + O2 + NADPH + H+ = taurine + NADP+ + H2O

-

-

1.5.1.23

tauropine + NAD+ + H2O = taurine + pyruvate + NADH

-

-

1.5.1.23

tauropine + NAD+ + H2O = taurine + pyruvate + NADH + H+

-

-

1.14.13.8

5 entries

1.5.1.23

2 entries

3.5.1.21

N-acetyl-taurine + H2O = taurine + acetate

-

-

3.5.1.24

taurochenodeoxycholate + H2O = chenodeoxycholate + taurin

649378

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholate + H2O = chenodeoxycholate + taurin

649378

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholate + H2O = chenodeoxycholate + taurin

649378

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = taurin + cholic acid

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurin + cholic acid

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurin + cholic acid

-

7SVG, 3D-view

3.5.1.24

3,12-dioxo-5beta-cholanoyltaurine + H2O = 3,12-dioxo-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3,12-dioxo-5beta-cholanoyltaurine + H2O = 3,12-dioxo-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3,12-dioxo-5beta-cholanoyltaurine + H2O = 3,12-dioxo-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3,7-dioxo-5beta-cholanoyltaurine + H2O = 3,7-dioxo-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3,7-dioxo-5beta-cholanoyltaurine + H2O = 3,7-dioxo-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3,7-dioxo-5beta-cholanoyltaurine + H2O = 3,7-dioxo-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3-oxo-5beta-cholanoyltaurine + H2O = 3-oxo-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3-oxo-5beta-cholanoyltaurine + H2O = 3-oxo-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3-oxo-5beta-cholanoyltaurine + H2O = 3-oxo-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyltaurine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyltaurine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyltaurine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha,7alpha,12alpha-trihydroxy-5beta-homocholan-24-oyltaurine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-homocholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha,7alpha,12alpha-trihydroxy-5beta-homocholan-24-oyltaurine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-homocholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha,7alpha,12alpha-trihydroxy-5beta-homocholan-24-oyltaurine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-homocholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyltaurine + H2O = 3alpha,7alpha-dihydroxy-5beta-cholestanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyltaurine + H2O = 3alpha,7alpha-dihydroxy-5beta-cholestanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyltaurine + H2O = 3alpha,7alpha-dihydroxy-5beta-cholestanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha,7alpha-dihydroxy-5beta-homocholanoyltaurine + H2O = 3alpha,7alpha-dihydroxy-5beta-homocholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha,7alpha-dihydroxy-5beta-homocholanoyltaurine + H2O = 3alpha,7alpha-dihydroxy-5beta-homocholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha,7alpha-dihydroxy-5beta-homocholanoyltaurine + H2O = 3alpha,7alpha-dihydroxy-5beta-homocholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha,7beta-dihydroxy-5beta-cholanoyltaurine + H2O = 3alpha,7beta-dihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha,7beta-dihydroxy-5beta-cholanoyltaurine + H2O = 3alpha,7beta-dihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha,7beta-dihydroxy-5beta-cholanoyltaurine + H2O = 3alpha,7beta-dihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha-hydroxy-12-oxo-5beta-cholanoyltaurine + H2O = 3alpha-hydroxy-12-oxo-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha-hydroxy-12-oxo-5beta-cholanoyltaurine + H2O = 3alpha-hydroxy-12-oxo-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha-hydroxy-12-oxo-5beta-cholanoyltaurine + H2O = 3alpha-hydroxy-12-oxo-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3alpha-hydroxy-7-oxo-5beta-cholanyltaurine + H2O = 3alpha-hydroxy-7-oxo-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3alpha-hydroxy-7-oxo-5beta-cholanyltaurine + H2O = 3alpha-hydroxy-7-oxo-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3alpha-hydroxy-7-oxo-5beta-cholanyltaurine + H2O = 3alpha-hydroxy-7-oxo-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3beta,7alpha-dihydroxy-5beta-cholanoyltaurine + H2O = 3beta,7alpha-dihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3beta,7alpha-dihydroxy-5beta-cholanoyltaurine + H2O = 3beta,7alpha-dihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3beta,7alpha-dihydroxy-5beta-cholanoyltaurine + H2O = 3beta,7alpha-dihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

3beta,7beta-dihydroxy-5beta-cholanoyltaurine + H2O = 3beta,7beta-dihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

3beta,7beta-dihydroxy-5beta-cholanoyltaurine + H2O = 3beta,7beta-dihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

3beta,7beta-dihydroxy-5beta-cholanoyltaurine + H2O = 3beta,7beta-dihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

cholyltaurine + H2O = cholic acid + taurine

-

2BJF, 3D-view

3.5.1.24

cholyltaurine + H2O = cholic acid + taurine

-

7SVF, 3D-view

3.5.1.24

cholyltaurine + H2O = cholic acid + taurine

-

7SVG, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = beta-muricholate + taurine

-

2BJF, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = beta-muricholate + taurine

-

7SVF, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = beta-muricholate + taurine

-

7SVG, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = taurine + beta-muricholic acid

-

2BJF, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = taurine + beta-muricholic acid

-

7SVF, 3D-view

3.5.1.24

tauro-beta-muricholic acid + H2O = taurine + beta-muricholic acid

-

7SVG, 3D-view

3.5.1.24

taurochenodeoxycholate + H2O = taurine + chenodeoxycholate

-

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholate + H2O = taurine + chenodeoxycholate

-

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholate + H2O = taurine + chenodeoxycholate

-

7SVG, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = 3alpha,7alpha-dihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = 3alpha,7alpha-dihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = 3alpha,7alpha-dihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = taurine + chenodeoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = taurine + chenodeoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurochenodeoxycholic acid + H2O = taurine + chenodeoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholate

-

2BJF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholate

-

7SVF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholate

-

7SVG, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholic acid

-

2BJF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholic acid

-

7SVF, 3D-view

3.5.1.24

taurocholate + H2O = taurine + cholic acid

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = cholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = cholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = cholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholate

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholate

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholate

-

7SVG, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholic acid

-

2BJF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholic acid

-

7SVF, 3D-view

3.5.1.24

taurocholic acid + H2O = taurine + cholic acid

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholate

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholate

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholate

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholate + H2O = taurine + deoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = 3alpha,12alpha-dihydroxy-5beta-cholanate + taurine

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = 3alpha,12alpha-dihydroxy-5beta-cholanate + taurine

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = 3alpha,12alpha-dihydroxy-5beta-cholanate + taurine

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = deoxycholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = deoxycholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = deoxycholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholate

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholate

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholate

-

7SVG, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

2BJF, 3D-view

3.5.1.24

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

7SVF, 3D-view

3.5.1.24

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

7SVG, 3D-view

3.5.1.24

taurolithocholic acid + H2O = lithocholate + taurine

-

2BJF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = lithocholate + taurine

-

7SVF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = lithocholate + taurine

-

7SVG, 3D-view

3.5.1.24

taurolithocholic acid + H2O = taurine + lithocholic acid

-

2BJF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = taurine + lithocholic acid

-

7SVF, 3D-view

3.5.1.24

taurolithocholic acid + H2O = taurine + lithocholic acid

-

7SVG, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

2BJF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

7SVF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

7SVG, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = ursodeoxycholate + taurine

-

2BJF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = ursodeoxycholate + taurine

-

7SVF, 3D-view

3.5.1.24

tauroursodeoxycholic acid + H2O = ursodeoxycholate + taurine

-

7SVG, 3D-view

3.5.1.24

114 entries

3.5.1.4

N-oleoyl taurine + H2O = oleic acid + taurine

-

-

3.5.1.6

2-ureidoethanesulfonic acid + H2O = taurine + CO2 + NH3

-

-

3.5.1.6

N-carbamoyl-taurine + H2O = taurine + CO2 + NH3

-

-

3.5.1.74

tauro (3alpha,5beta,7beta,12alpha)-3,7,12-trihydroxycholan-24-oic amide + H2O = taurine + (3alpha,5beta,7beta,12alpha)-3,7,12-trihydroxycholan-24-oic acid

-

-

3.5.1.74

tauro-beta-muricholic acid + H2O = taurine + beta-muricholic acid

-

-

3.5.1.74

taurochenodeoxycholic acid + H2O = chenodeoxycholate + taurine

-

-

3.5.1.74

taurocholic acid + H2O = taurine + cholic acid

-

-

3.5.1.74

taurodeoxycholic acid + H2O = taurine + deoxycholic acid

-

-

3.5.1.74

taurohyocholic acid + H2O = taurine + hyocholic acid

-

-

3.5.1.74

taurohyodeoxycholic acid + H2O = taurine + hyodeoxycholic acid

-

-

3.5.1.74

tauroursodeoxycholic acid + H2O = taurine + ursodeoxycholic acid

-

-

3.5.1.6

2 entries

3.5.1.74

8 entries

3.5.1.99

N-oleoyltaurine + H2O = taurine + oleic acid

-

-

3.5.3.7

taurocyamine + H2O = taurine + urea

209442, -

-

4.1.1.122

L-cysteate = taurine + CO2

-

-

4.1.1.29

Cysteic acid = 2-Aminoethane sulfonate + CO2

-

-

7.6.2.14

ATP + H2O + taurine-[sulfonate-binding protein][side 1] = ADP + phosphate + taurine[side 2] + [sulfonate-binding protein][side 1]

-

-

7.6.2.7

ATP + H2O + taurine/out = ADP + phosphate + taurine/in

-

-

Activator in Enzyme-catalyzed Reactions (5 results)

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Show Activating Compound (5 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

3.5.3.18

-

697831

-

3.5.3.18

-

697831

-

3.5.3.18

2 entries

3.6.1.15

activates the enzyme, and acts as antagonist and reduces the hypochlorous acid toxicity

671005

-

4.2.1.20

0.5 M taurine activates the enzyme 3fold in the absence of monovalent cations

729226

-

7.4.2.2

5 mM, 147% of initial L-proline uptake

766566

-

Inhibitor in Enzyme-catalyzed Reactions (12 results)

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Show Inhibitors (12 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.4.1.2

-

391560

-

1.4.3.13

-

686366

-

2.5.1.18

about 19% inhibition at 0.1 mM

759335

-

2.6.1.19

i.e. taurine, competitive

662526

-

3.2.1.33

slight inhibition

171379

-

3.5.1.24

uncompetitive inhibition of glycocholic acid hydrolysis

670898

2BJF, 3D-view

3.5.1.24

uncompetitive inhibition of glycocholic acid hydrolysis

670898

7SVF, 3D-view

3.5.1.24

uncompetitive inhibition of glycocholic acid hydrolysis

670898

7SVG, 3D-view

3.5.1.24

3 entries

3.7.1.1

-

776500

-

5.1.1.15

-

2087

-

6.3.2.1

-

978, 979

-

6.3.2.1

52% inhibition at 1 mM

977

-

6.3.2.1

2 entries

3D Structure of Enzyme-Ligand-Complex (PDB) (69 results)

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Show 3D Structure of Enzyme-Ligand-Complex (PDB) (69 entries)

EC NUMBER

ENZYME 3D STRUCTURE

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

1GQW, 3D-view

1.14.11.17

1GY9, 3D-view

1.14.11.17

1OS7, 3D-view

1.14.11.17

1OTJ, 3D-view

1.14.11.17

6EDH, 3D-view

1.14.11.17

40 entries

2.7.7.7

4M8O, 3D-view

3.2.1.18

4FOQ, 3D-view

3.4.16.4

3V39, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

2BJF, 3D-view

3.5.1.24

7SVF, 3D-view

3.5.1.24

7SVG, 3D-view

3.5.1.24

24 entries

3.5.2.6

4FCF, 3D-view

3.5.4.25

2BZ1, 3D-view

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (8 results)

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Show Turnover Number (8 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.14.11.17

0.74

-

mutant D101E, 30°C

688192

1.14.11.17

1.1

-

mutant H255E, 30°C

688192

1.14.11.17

2.7

-

mutant H255Q, 30°C

688192

1.14.11.17

3

-

wild type enzyme

671301

1.14.11.17

3.3

-

wild-type, 30°C

688192

1.14.11.17

5 entries

2.3.1.280

14.8

-

pH 7.5, 25°C

749881

2.6.1.120

0.51

-

cosubstrate 2-oxoglutarate, pH 8, temperature not specified in the publication

763265

2.6.1.55

3.7

-

pH 7.2, 37°C, recombinant enzyme

758762

K_M Value (34 results)

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Show KM Value (34 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.14.11.17

0.019

-

mutant H255E, 30°C

688192

1.14.11.17

0.019

-

wild-type, 30°C

688192

1.14.11.17

0.0194

-

-

701264

1.14.11.17

0.021

-

mutant H255Q, 30°C

688192

1.14.11.17

0.052

-

wild type enzyme

671301

1.14.11.17

0.055

-

-

285263

1.14.11.17

0.061

-

mutant D101E, 30°C

688192

1.14.11.17

7 entries

1.4.99.2

20

-

-

395284, 395285

1.5.1.23

15

-

-

13438

1.5.1.23

21.3

-

-

13439

1.5.1.23

35.7

-

-

13440

1.5.1.23

37

-

-

13437

1.5.1.23

44.4

-

-

13436

1.5.1.23

5 entries

1.97.1.13

0.112

-

at pH 8.0 and 80°C

772986

2.1.4.1

392

-

alpha-transamidinase

485972

2.3.1.280

18.9

-

pH 7.5, 25°C

749881

2.3.1.65

0.6

-

-

487367

2.3.1.65

0.8

-

+ 0.05 mM deoxycholoyl-CoA

487368

2.3.1.65

0.8

2.5

-

487371

2.3.1.65

0.83

-

rats fed with cellulose

487371

2.3.1.65

1

-

37°C, pH 8.4

675804

2.3.1.65

1.01

-

mutant enzyme BAAT-SKL, at pH 8.4 and 37°C

757369

2.3.1.65

1.02

-

rats fed with pectin

487371

2.3.1.65

1.77

-

mutant enzyme BAAT-S, at pH 8.4 and 37°C

757369

2.3.1.65

1.86

-

wild type enzyme, at pH 8.4 and 37°C

757369

2.3.1.65

1.9

-

recombinant enzyme, expressed in Escherichia coli

487373

2.3.1.65

2

-

-

659664

2.3.1.65

6.7

-

-

487365

2.3.1.65

12 entries

2.6.1.120

12

-

cosubstrate 2-oxoglutarate, pH 8, temperature not specified in the publication

763265

2.6.1.55

1.1

-

pH 7.2, 37°C, recombinant enzyme

758762

2.6.1.55

12

-

-

636679

2.6.1.55

12

-

pH 8.0, 37°C

636678

2.6.1.77

5.3

-

pH 9.0, 37°C

737516

2.6.1.77

7.1

-

pH 9.0, 35°C

640197

2.6.1.55

3 entries

2.6.1.77

2 entries

K_i Value (2 results)

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Show KI Value (2 entries)

EC NUMBER

KI VALUE [MM]

KI VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.6.1.19

68

-

pH 8.6, 25°C

662526

3.5.1.24

2.5

-

pH 8.0, 50°C

670898

References & Links

Literature References (112)

top print hide

Show Reference (112 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

977

374975

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1979

Miyatake, K.; Nakano, Y.; Kitaoka, S.

Methods Enzymol.

62

215-219

978

357689

Enzymological properties of pantothenate synthetase from Escherichia coli B

1978

Miyatake, K.; Nakano, Y.; Kitaoka, S.

J. Nutr. Sci. Vitaminol.

24

243-253

979

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Some properties of pantothenate synthetase partially purified from Escherichia coli B

1975

Miyatake, K.; Nakano, Y.; Kitaoka, S.

Bull. Univ. Osaka Prefect

27

57-67

2087

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Mechanism of inactivation of alpha-amino-epsilon-caprolactam racemase by alpha-amino-delta-valerolactam

1985

Ahmed, S.A.; Esaki, N.; Tanaka, H.; Soda, K.

Agric. Biol. Chem.

49

2991-2997

13292

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Distribution of opine dehydrogenases and lactate dehydrogenase activities in marine animals

1993

Sato, M.; Takeuchi, M.; Kanno, N.; Nagahisa, E.; Sato, Y.

Comp. Biochem. Physiol. B

106

955-960

13300

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Opine oxidoreductases in brachiopods, bryozoans, phoronids and molluscs

1991

Hammen, C.S.; Bullock, R.C.

Biochem. Syst. Ecol.

19

263-269

13434

3435647

A specific enzymatic method for determination of taurine

1987

Gäde, G.

Biol. Chem. Hoppe-Seyler

368

1519-1523

13435

3769931

Purification and properties of tauropine dehydrogenase from the shell adductor muscle of the ormer, Haliotis lamellosa

1986

Gäde, G.

Eur. J. Biochem.

160

311-318

13436

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Characterization and physiological role of tauropine dehydrogenase and lactate dehydrogenase from muscle of abalone, Haliotis discus hannai

1991

Sato, M.; Takeuchi, M.; Kanno, N.; Nagahisa, E.; Sato, Y.

Tohoku J. Agric. Res.

41

83-95

13437

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Purification and characterization of tauropine dehydrogenase from the marine sponge Halichondria japonica Kadota (demospongia)

1997

Kanno, N.; Sato, M.; Nagahisa, E.; Sato, Y.

Fish. Sci.

63

414-420

13438

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Purification and properties of tauropine dehydrogenase from a red alga Rhodoglossum japonicum

1993

Sato, M.; Takeuchi, M.; Kanno, N.; Nagahisa, E.; Sato, Y.

Hydrobiologia

260/261

673-678

13439

10075484

Tauropine dehydrogenase from the starfish Asterina pectinifera (echinodermata: asteroidea): presence of opine production pathway in a deuterostome invertebrate

1998

Kan-no, N.; Sato, M.; Yokoyama, T.; Nagahisa, E.; Sato, Y.

Comp. Biochem. Physiol. B

121

323-332

13440

8840516

Tauropine dehydrogenase from the sandworm Arabella iricolor (polychaeta: errantia): purification and characterization

1996

Kanno, N.; Sato, M.; Nagahisa, E.; Sato, Y.

Comp. Biochem. Physiol. B

114

409-416

171379

5805288

Purification and properties of rabbit muscle amylo-1,6-glucosidase-oligo-1,4->1,4-transferase

1969

Nelson, T.E.; Kolb, E.; Larner, J.

Biochemistry

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1419-1428

209442

6678939

Taurocyamine-utilizing mutants from a wild-type strain of Pseudomonas

1983

Yorifuji, T.; Shiritani, Y.; Eguchi, S.; Yonaha, K.

J. Appl. Biochem.

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375-381

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Deletion analysis of the Escherichia coli taurine and alkanesulfonate transport systems

2000

Eichhorn, E.; van der Ploeg, J.R.; Leisinger, T.

J. Bacteriol.

182

2687-2795

210349

9782504

Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates

1998

Van der Ploeg, J.R.; Cummings, N.J.; Leisinger, T.; Connerton, I.F.

Microbiology

144

2555-2561

210350

8808933

Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source

1996

Van der Ploeg, J.R.; Weiss, M.A.; Saller, E.; Nashimoto, H.; Saito, N.; Kertesz, M.A.; Leisinger, T.

J. Bacteriol.

178

5438-5446

285263

9287300

Characterization of alpha-ketoglutarate-dependent taurine dioxygenase from Escherichia coli

1997

Eichhorn, E.; Van der Ploeg, J.R.; Kertesz, M.A.; Leisinger, T.

J. Biol. Chem.

272

23031-23036

288059

13712439

Enzymatic studies on the metabolism of beta-alanine

1961

Hayaishi, O.; Nishizuka, Y.; Tatibana, M.; Takeshita, M.; Kuno, S.

J. Biol. Chem.

236

781-790

391560

6671673

Characterization of L-glutamate dehydrogenase activity of axenically grown Acanthamoeba culbertsoni

1983

Singh, U.S.; Rao, V.K.M.

Indian J. Biochem. Biophys.

20

146-148

394698

13979247

Oxidation of hypotaurine in rat liver

1962

Sumizu, K.

Biochim. Biophys. Acta

63

210 - 212

395284

3657561

Taurine dehydrogenase

1987

Kondo, H.; Ishimoto, M.

Methods Enzymol.

143

496-499

395285

4724302

Purification and some properties of taurine dehydrogenase from a bacterium

1973

Kondo, H.; Kagotani, K.; Oshima, M.; Ishimoto, M.

J. Biochem.

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1269-1278

485972

8035648

Synthesis of neuroactive guanidino compounds by rat kidney L-arginine:glycine amidinotransferase

1994

Watanabe, Y.; Van Pilsum, J.F.; Yokoi, I.; Mori, A.

Life Sci.

55

351-358

487364

422567

The co-purification and common identity of cholyl CoA:glycine- and cholyl CoA: taurine-N-acyltransferase activities from bovine liver

1979

Vessey, D.A.

J. Biol. Chem.

254

2059-2063

487365

7372637

Kinetic characterization of cholyl-CoA glycine-taurine N-acyltransferase from bovine liver

1980

Czuba, B.; Vessey, D.A.

J. Biol. Chem.

255

5296-5299

487366

3700392

Structural characterization of cholylcoenzyme A: glycine-taurine N-acyltransferase and a covalent substrate intermediate

1986

Czuba, B.; Vessey, D.A.

J. Biol. Chem.

261

6260-6263

487367

6884990

Purification and characterization of amino-acid N-choloyltransferase from human liver

1983

Kimura, M.; Okuno, E.; Inada, J.; Ohyama, H.; Kido, R.

Hoppe-Seyler's Z. Physiol. Chem.

364

637-645

487368

624713

Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from rat liver

1978

Killenberg, P.G.; Jordan, J.T.

J. Biol. Chem.

253

1005-1010

487369

7295754

Identification of a unique mammalian species of cholyl-CoA: amino acid N-acyltransferase

1981

Czuba, B.; Vessey, D.A.

Biochim. Biophys. Acta

665

612-614

487371

7918332

Dietary modifications of the biliary bile acid glycine:taurine ratio and activity of hepatic bile acid-CoA:amino acid N-acyltransferase (EC 2.3.1) in the rat

1994

Ide, T.; Kano, S.; Murata, M.; Yanagita, T.; Sugano, M.

Br. J. Nutr.

72

93-100

487372

12239217

Conserved residues in the putative catalytic triad of human bile acid coenzyme A:amino acid N-acyltransferase

2002

Sfakianos, M.K.; Wilson, L.; Sakalian, M.; Falany, C.N.; Barnes, S.

J. Biol. Chem.

277

47270-47275

487373

9215542

Cloning, expression, and chromosomal localization of mouse liver bile acid CoA:amino acid N-acyltransferase

1997

Falany, C.N.; Fortinberry, H.; Leiter, E.H.; Barnes, S.

J. Lipid Res.

38

1139-1148

636677

5012173

Crystalline taurine: alpha-ketoglutarate aminotransferase from Achromobacter superficialis

1972

Toyama, S.; Misono, H.; Soda, K.

Biochem. Biophys. Res. Commun.

46

1374-1379

636678

3003495

Taurine-glutamate transaminase

1985

Yonaha, K.; Toyama, S.; Soda, K.

Methods Enzymol.

113

102-108

636679

629994

Properties of taurine: alpha-ketoglutarate aminotransferase of Achromobacter superficialis. Inactivation and reactivation of enzyme

1978

Toyama, S.; Misono, H.; Soda, K.

Biochim. Biophys. Acta

523

75-81

636680

5058441

Occurrence of taurine: alpha-ketoglutarate aminotransferase in bacterial extracts

1972

Toyama, S.; Soda, K.

J. Bacteriol.

109

533-538

640197

11082195

Biochemical and molecular characterization of taurine:pyruvate transaminase from the anaerobe Bilophila wadsworthia

2000

Laue, H.; Cook, A.M.

Eur. J. Biochem.

267

6841-6848

640198

12471498

Dissimilation of the C2 sulfonates

2002

Cook, A.M.; Denger, K.

Arch. Microbiol.

179

1-6

640199

11728723

Genetic analysis of a Rhodobacter capsulatus gene region involved in utilization of taurine as a sulfur source

2001

Masepohl, B.; Fuhrer, F.; Klipp, W.

FEMS Microbiol. Lett.

205

105-111

640200

16535664

Taurine-sulfur assimilation and taurine-pyruvate aminotransferase activity in anaerobic bacteria

1997

Chien, C.C.; Leadbetter, E.R.; Godchaux, W.III.

Appl. Environ. Microbiol.

63

3021-3024

649378

12450872

Quantitative determination of bile salt hydrolase activity in bacteria isolated from the small intestine of chickens

2002

Knarreborg, A.; Engberg, R.M.; Jensen, S.K.; Jensen, B.B.

Appl. Environ. Microbiol.

68

6425-6428

656739

15073291

Enzymes and genes of taurine and isethionate dissimilation in Paracoccus denitrificans

2004

Bruggemann, C.; Denger, K.; Cook, A.M.; Ruff, J.

Microbiology

150

805-816

657592

14602592

Use of bacterial gamma-glutamyltranspeptidase for enzymatic synthesis of gamma-D-glutamyl compounds

2003

Suzuki, H.; Izuka, S.; Minami, H.; Miyakawa, N.; Ishihara, S.; Kumagai, H.

Appl. Environ. Microbiol.

69

6399-6404

657933

11955067

X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates

2002

Elkins, J.M.; Ryle, M.J.; Clifton, I.J.; Dunning Hotopp, J.C.; Lloyd, J.S.; Burzlaff, N.I.; Baldwin, J.E.; Hausinger, R.P.; Roach, P.L.

Biochemistry

41

5185-5192

657996

12741810

Substrate-induced conformational changes in Escherichia coli taurine/alpha-ketoglutarate dioxygenase and insight into the oligomeric structure

2003

O'Brien, J.R.; Schuller, D.J.; Yang, V.S.; Dillard, B.D.; Lanzilotta, W.N.

Biochemistry

42

5547-5554

658130

15924433

Kinetic dissection of the catalytic mechanism of taurine:alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli

2005

Price, J.C.; Barr, E.W.; Hoffart, L.M.; Krebs, C.; Bollinger, J.M., Jr.

Biochemistry

44

8138-8147

658567

-

Salt-tolerant gamma-glutamyltranspeptidase from Bacillus subtilis 168 with glutaminase activity

2003

Minami, H.; Suzuki, H.; Kumagai, H.

Enzyme Microb. Technol.

32

431-438

658975

14746461

Direct detection of oxygen intermediates in the non-heme Fe enzyme taurine/alpha-ketoglutarate dioxygenase

2004

Proshlyakov, D.A.; Henshaw, T.F.; Monterosso, G.R.; Ryle, M.J.; Hausinger, R.P.

J. Am. Chem. Soc.

126

1022-1023

658984

15225039

EXAFS spectroscopic evidence for an Fe:O Unit in the Fe(IV) intermediate observed during oxygen activation by taurine:alpha-ketoglutarate dioxygenase

2004

Riggs-Gelasco, P.J.; Price, J.C.; Guyer, R.B.; Brehm, J.H.; Barr, E.W.; Bollinger, J.M., Jr.; Krebs, C.

J. Am. Chem. Soc.

126

8108-8109

659246

12810727

The Human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine

2003

O'Byrne, J.; Hunt, M.C.; Rai, D.K.; Saeki, M.; Alexson, S.E.H.

J. Biol. Chem.

278

34237-34244

659664

12951368

Rat liver: Expression, characterization, and peroxisomal localization

2003

He, D.; Barnes, S.; Falany, C.N.

J. Lipid Res.

44

2242-2249

662526

14567543

Kinetic studies of the inhibition of GABA-T by gamma-vinyl GABA and taurine

2003

Sulaiman, S.A.J.; Suliman, F.E.O.; Barghouthi, S.

J. Enzyme Inhib. Med. Chem.

18

297-301

662780

15184572

Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source

2004

Denger, K.; Ruff, J.; Schleheck, D.; Cook, A.M.

Microbiology

150

1859-1867

662781

15184574

Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides

2004

Novak, R.T.; Gritzer, R.F.; Leadbetter, E.R.; Godchaux, W.

Microbiology

150

1881-1891

664237

113035

Catabolism of taurine in Pseudomonas aeruginosa

1979

Shimamoto, G.; Berk, R.S.

Biochim. Biophys. Acta

569

287-292

670898

16307764

Xanthomonas maltophilia CBS 897.97 as a source of new 7beta- and 7alpha-hydroxysteroid dehydrogenases and cholylglycine hydrolase: improved biotransformations of bile acids

2006

Pedrini, P.; Andreotti, E.; Guerrini, A.; Dean, M.; Fantin, G.; Giovannini, P.P.

Steroids

71

189-198

671005

14991940

Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver

2004

Li, J.X.; Pang, Y.Z.; Tang, C.S.; Li, Z.Q.

World J. Gastroenterol.

10

694-698

671301

16643838

An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation

2006

Luo, L.; Pappalardi, M.B.; Tummino, P.J.; Copeland, R.A.; Fraser, M.E.; Grzyska, P.K.; Hausinger, R.P.

Anal. Biochem.

353

69-74

671638

15883781

Isethionate as a product from taurine during nitrogen-limited growth of Klebsiella oxytoca TauN1

2005

Styp von Rekowski, K.; Denger, K.; Cook, A.M.

Arch. Microbiol.

183

325-330

671648

16802176

N-Acetyltaurine dissimilated via taurine by Delftia acidovorans NAT

2006

Mayer, J.; Denger, K.; Smits, T.H.; Hollemeyer, K.; Groth, U.; Cook, A.M.

Arch. Microbiol.

186

61-67

671717

16165092

Kinetic and spectroscopic investigation of CoII, NiII, and N-oxalylglycine inhibition of the FeII/alpha-ketoglutarate dioxygenase, TauD

2005

Kalliri, E.; Grzyska, P.K.; Hausinger, R.P.

Biochem. Biophys. Res. Commun.

338

191-197

671956

2261454

Characterization of vanadium bromoperoxidase from Macrocystis and Fucus: reactivity of vanadium bromoperoxidase toward acyl and alkyl peroxides and bromination of amines

1990

Soedjak, H.S.; Butler, A.

Biochemistry

29

7974-7981

673044

17180236

Can the peroxosuccinate complex in the catalytic cycle of taurine/alpha-ketoglutarate dioxygenase (TauD) act as an alternative oxidant?

2007

de Visser, S.P.

Chem. Commun. (Camb. )

2007

171-173

673443

-

Mechanism of taurine: alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli

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