Ligand GDP

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Basic Ligand Information

Molecular Structure
Picture of GDP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H15N5O11P2
GDP
QGWNDRXFNXRZMB-UUOKFMHZSA-N
Synonyms:
D-GDP, guanosine 5'-diphosphate, guanosine 5'-O-diphosphate, guanosine diphosphate, ppG

Show all pahtways known for Show all pathways known for GDP

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (50 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDP + 3-phospho-D-glyceroyl 1-phosphate = GTP + 3-phospho-D-glycerate
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GDP + [phosphate]n = GMP + [phosphate]n+1
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ATP + GDP = AMP + guanosine 3'-diphosphate 5'-diphosphate
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GDP + alpha-D-mannose 1-phosphate = phosphate + GDP-mannose
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5'-triphospho-mRNA + GDP = diphosphate + guanosine 5'-triphospho-mRNA
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GDP + H2O = GMP + phosphate
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GDP + H2O = GMP + phosphate
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GDP + H2O = GMP + phosphate
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GDP + H2O = GMP + phosphate
show the reaction diagram
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GDP + H2O = GMP + phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (287 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDPmannose + tRNAAsp-queuosine = GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine
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GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol
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GDP-mannose + GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-dicis,octatrans-undecaprenol = GDP + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-dicis,octatrans-undecaprenol
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GDP-D-mannose + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = GDP + D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol
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GDP-glucose + 3-phospho-D-glycerate = GDP + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate
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GDP-mannose + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate = GDP + 2-(2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl)-3-phospho-D-glycerate
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GDP-beta-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol = GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
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GDP-D-mannose + (glucomannan)n = GDP + (glucomannan)n+1
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GDP-D-mannuronate + (alginate)n = GDP + (alginate)n+1
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GDP-beta-L-colitose + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = GDP + alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine
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GDP-glucose + glucose 6-phosphate = GDP + alpha,alpha-trehalose 6-phosphate
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GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = GDP + alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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GDP-alpha-D-mannose + alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = GDP + alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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GDP-glucose + glucose 6-phosphate = GDP + alpha,alpha-trehalose 6-phosphate
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GDP-mannose + heteroglycan = GDP + 1,2(or 1,3)-alpha-D-mannosylheteroglycan
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GDP-alpha-D-mannose + 1,2-di-O-C16/C18:1-(alpha-D-glucopyranosyluronic acid)-(1->3)-glycerol = GDP + 1,2-di-O-C16/C18:1-(alpha-D-mannopyranosyl)-(1->4)-(alpha-D-glucopyranosyluronic acid)-(1->3)-glycerol
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GTP + 5-hydroxy-L-lysine = GDP + O-phosphohydroxy-L-lysine
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GTP + AMP = GDP + ADP
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GMP + [phosphate]n = GDP + [phosphate]n-1
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guanosine 3'-diphosphate 5'-diphosphate + H2O = GDP + diphosphate
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GDPmannose + phosphate = GDP + mannose 1-phosphate
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GDP-beta-L-galactose + phosphate = GDP + beta-L-galactose 1-phosphate
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GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP
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GDP-mannose + endogenous acceptor molecule = GDP + endogenous acceptor molecule modified
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ppGpp + H2O = ppG + diphosphate
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GDP-mannosylpyranose + H2O = alpha-D-mannopyranose + GDP
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GDP-glucose + H2O = GDP + D-glucose
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GTP + H2O = GDP + phosphate
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GTP + H2O = GDP + phosphate
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GTP + H2O + a kinesin associated with a microtubule at position n = GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
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GTP + acetate + CoA = GDP + phosphate + acetyl-CoA
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L-glutamate + GTP + coenzyme F420-0 = GDP + phosphate + coenzyme gamma-F420-1
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GTP + tetrahydromethanopterin + L-glutamate = GDP + phosphate + 5,6,7,8-tetrahydrosarcinapterin
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Substrate in Enzyme-catalyzed Reactions (206 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDP + reduced thioredoxin = dGDP + oxidized thioredoxin + H2O
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S-adenosyl-L-methionine + GDP = S-adenosyl-L-homocysteine + m7GDP
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alpha,alpha-trehalose + GDP = GDP-alpha-D-glucose + D-glucose
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dimethylallyl diphosphate + GDP = ?
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dimethylallyl diphosphate + GDP = ?
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D-fructose 6-phosphate + GDP = D-fructose 1,6-bisphosphate + GMP
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GDP + D-glucose = GMP + D-glucose 6-phosphate
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GDP + adenosine = GMP + AMP
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GDP + phosphoenolpyruvate = GTP + pyruvate
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GDP + 3-phospho-D-glyceroyl 1-phosphate = GTP + 3-phospho-D-glycerate
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GDP + Nomega-phospho-L-Arg = GTP + L-Arg
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GDP + phosphoramide = GTP + NH3
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GDP + trans-farnesyl diphosphate = GMP + trans-farnesyl triphosphate
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GDP + [phosphate]n = GMP + [phosphate]n+1
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ATP + GDP = diphosphate + ?
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GDP + alpha-D-mannose 1-phosphate = phosphate + GDP-mannose
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GDP + phosphate = phosphate + GDP
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p-tRNAHis + ATP + GDP = ?
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poly(G) + GDP = poly(G)+1 + phosphate
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GDP + H2O = GMP + phosphate
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GDP + H2O = ?
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GDP + H2O = ?
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glucose + GDP = glucose 6-phosphate + GMP
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GDP + H2O = ?
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GDP + H2O = ?
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GDP + H2O = GMP + phosphate
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adenosine 5'-phosphoimidazolide + GDP = imidazole + A(5')p3(5')G
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GDP + H2O = GMP + phosphate
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GDP + H2O = GMP + phosphate
show the reaction diagram
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GDP + H2O = GMP + phosphate
show the reaction diagram
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GDP + H2O = ?
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GDP + H2O = GMP + phosphate
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GDP + phosphate + acetyl-CoA = GTP + acetate + CoA
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GDP + phosphate + acetyl-CoA = GTP + acetate + CoA
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ATP + GDP = P1-(5'-adenosyl),P3-(5'-guanosyl)triphosphate + diphosphate
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GDP + phosphate + Na+/out = GTP + H2O + Na+/in
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Product in Enzyme-catalyzed Reactions (1564 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[elongator tRNAMet]-cytidine34 + GTP + acetyl-CoA = [elongator tRNAMet]-N4-acetylcytidine34 + GDP + phosphate + coenzyme A
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GTP + H2O = GDP + phosphate
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GTP + citrate + CoA = GDP + phosphate + acetyl-CoA + oxaloacetate
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GDP-glucose + (1,4-alpha-D-glucosyl)n = GDP + (1,4-alpha-D-glucosyl)n+1
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GDPmannose + tRNAAsp-queuosine = GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine
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GDP-glucose + D-fructose = GDP + sucrose
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GDP-glucose + D-fructose 6-phosphate = GDP + sucrose 6-phosphate
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GDP-glucose + indoxyl = GDP + indican
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GDP-mannose + D-fructose 6-phosphate = GDP + beta-D-fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
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GDP-D-mannose + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = GDP + D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol
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GDP-glucose + D-glycerate = 2-O-(alpha-D-glucopyranosyl)-D-glycerate + GDP
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GDP-mannose + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate = GDP + 2-(2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl)-3-phospho-D-glycerate
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GDP-glucose + (1,4-beta-D-glucosyl)n = GDP + (1,4-beta-D-glucosyl)n+1
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GDP-D-mannose + (glucomannan)n = GDP + (glucomannan)n+1
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GDP-D-mannuronate + (alginate)n = GDP + (alginate)n+1
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GDP-alpha-D-glucose + validoxylamine A = GDP + validamycin A
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