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BRENDA support

Ligand pheophorbide a

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Basic Ligand Information

Molecular Structure
Picture of pheophorbide a (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C35H36N4O5
pheophorbide a
NSFSLUUZQIAOOX-QEWKCGBTSA-N
Synonyms:
2-vinyl-4-ethyl chlorophyllide a, Pheophorbide

Related pathways

Pathway Source
Pathways
MetaCyc
chlorophyll a degradation I, chlorophyll a degradation II, chlorophyll a degradation III

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pheophorbide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = red chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster
show the reaction diagram
-
pheophorbide a + H2O = pyropheophorbide a + methanol + CO2
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,4-divinyl chlorophyllide a + NADPH + H+ = 2-vinyl-4-ethyl chlorophyllide a + NADP+
show the reaction diagram
-
pheophytin a + H2O = phytol + pheophorbide
show the reaction diagram
-
chlorophyllide a + 2 H+ = pheophorbide a + Mg2+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pheophorbide a + geranylgeranyl diphosphate = ?
show the reaction diagram
-
pheophorbide a + H2O = pyropheophorbide a + methanol + CO2
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,4-divinyl chlorophyllide a + NADPH + H+ = 2-vinyl-4-ethyl chlorophyllide a + NADP+
show the reaction diagram
-
chlorophyllide a + 2 H+ = pheophorbide a + Mg2+
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stronger inhibitor than the corresponding Mg-chelate
-
allosteric inhibitor
-

Enzyme Kinetic Parameters

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.006
-
pH 7.0, 24°C, recombinant enzyme

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0002
-
pH and temperature not specified in the publication
0.0666
-
at pH 5.5 and 37°C

References & Links

Links to other databases for pheophorbide a

EXTERNAL LINKS