Any feedback?
Please rate this page
(ligand.php)
(0/150)

BRENDA support

Ligand acetic acid

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of acetic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C2H4O2
acetic acid
QTBSBXVTEAMEQO-UHFFFAOYSA-N
 Download
Synonyms:
acetate, acetic acid', carboxymethyl-dethia-CoA, CH3CO2-, CH3COO-, CH3COOH

Related pathways

Pathway Source
Pathways
BRENDA
acetate fermentation, acetyl CoA biosynthesis, aerobic toluene degradation, aflatoxin biosynthesis, alanine metabolism more
KEGG
Alcoholic liver disease, Biosynthesis of secondary metabolites, C5-Branched dibasic acid metabolism, Carbohydrate digestion and absorption, Carbon fixation pathways in prokaryotes more
MetaCyc
(S)-lactate fermentation to propanoate, acetate and hydrogen, 1,2-propanediol biosynthesis from lactate (engineered), 11-oxyandrogens biosynthesis, 2,6-dinitrotoluene degradation, 2-nitrotoluene degradation more


Show all pahtways known for Show all BRENDA pathways known for acetic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (39 results)

top print hide
EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetate + H+ + reduced ferredoxin = acetaldehyde + H2O + oxidized ferredoxin
show the reaction diagram
-
arsenate + acetate = arsenite + ?
show the reaction diagram
-
L-cystathionine + acetate = O-acetyl-L-serine + L-homocysteine
show the reaction diagram
-
acetate + propanoyl-CoA = acetyl-CoA + propanoate
show the reaction diagram
-
5-hydroxypentanoyl-CoA + acetate = acetyl-CoA + 5-hydroxypentanoate
show the reaction diagram
-
acetate + oxalyl-CoA = acetyl-CoA + oxalate
show the reaction diagram
-
acetate = 2-oxoethanal + H2O
show the reaction diagram
ATP + acetate + CoA = ADP + phosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + citrate (pro-3S)-lyase = ?
show the reaction diagram
-
ATP + acetate + CoA = ADP + phosphate + acetyl-CoA
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (560 results)

top print hide
EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-lactate + O2 = acetate + CO2 + H2O
show the reaction diagram
-
(S)-lactate + O2 = acetate + CO2 + H2O
show the reaction diagram
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
Gly + H2O + O2 = acetate + NH3 + H2O2
show the reaction diagram
-
S-adenosyl-L-methionine + precorrin-5 + H2O = S-adenosyl-L-homocysteine + precorrin-6A + acetate
show the reaction diagram
- , 3209, 644278
-
acetyl-CoA + H2O = acetate + CoA
show the reaction diagram
-
malonate + acetyl-[acyl-carrier protein] = acetate + malonyl-[acyl-carrier protein]
show the reaction diagram
-
-
acetyl-CoA + alcohol = CoA + acetate
show the reaction diagram
-
-
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate
show the reaction diagram
-
-
O-acetyl-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH = [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + acetate
show the reaction diagram
-
O3-acetyl-L-serine + isoxazolin-5-one = 3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate
show the reaction diagram
-
-
O3-acetyl-L-serine + isoxazolin-5-one = 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate
show the reaction diagram
-
-
O3-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate
show the reaction diagram
-
-
O3-acetyl-L-serine + 3,4-dihydroxypyridine = 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate
show the reaction diagram
-
-
2 O3-acetyl-L-serine + 2 uracil = 3-(uracil-1-yl)-L-alanine + 3-(uracil-3-yl)-L-alanine + 2 acetate
show the reaction diagram
-
-
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate
show the reaction diagram
-
-
O-acetyl-L-serine + hydroxyurea = O-ureido-L-serine + acetate
show the reaction diagram
-
-
D-glucose + acetyl phosphate = D-glucose 6-phosphate + acetate
show the reaction diagram
-
-
ADP + acetyl phosphate = ATP + acetate
show the reaction diagram
-
acetyl-CoA + citrate = acetate + (3S)-citryl-CoA
show the reaction diagram
-
acetyl-[acyl-carrier protein] + citramalate = citramalyl-[acyl-carrier protein] + acetate
show the reaction diagram
-
-
acetyl-CoA + malonate = acetate + malonyl-CoA
show the reaction diagram
-
-
3-O-acetylpapaveroxine + H2O = narcotine hemiacetal + acetate
show the reaction diagram
-
-
ethyl acetate + H2O = acetate + ethanol
show the reaction diagram
-
-
methyl acetate + H2O = methanol + acetate
show the reaction diagram
-
-
peracetic acid = acetic acid + H2O
show the reaction diagram
-
5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate
show the reaction diagram
-
4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate
show the reaction diagram
646028, -
-
3,4-diacetoxybutynylbithiophene + H2O = 3-hydroxy-4-acetoxybutynylbithiophene + acetate
show the reaction diagram
-
-
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate
show the reaction diagram
-
-
acetylated rhamnogalacturonan I + H2O = acetate + deacetylated rhamnogalacturonan I
show the reaction diagram
-
-
acetyl-CoA + H2O = CoA + acetate
show the reaction diagram
-
[citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate
show the reaction diagram
-
Phosphonoacetate + H2O = acetate + phosphate
show the reaction diagram
-
-
N4-acetylcytidine + H2O = cytidine + acetate
show the reaction diagram
-
-
N,N'-diacetylchitobiose + H2O = beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine + acetate
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
N-acetyl-D-glucosamine + H2O = D-glucosamine + acetate
show the reaction diagram
-
N-acetyl-LL-2,6-diaminoheptanedioate + H2O = acetate + LL-2,6-diaminoheptanedioate
show the reaction diagram
-
-
acetamide + H2O = acetate + NH3
show the reaction diagram
-
-
4-acetamidobutanoyl-CoA + H2O = acetate + 4-aminobutanoyl-CoA
show the reaction diagram
-
N-acetyl-D-glutamate + H2O = acetate + D-glutamate
show the reaction diagram
-
N2-acetyl-L-citrulline + H2O = L-citrulline + acetate
show the reaction diagram
-
-
acetonitrile + 2 H2O = acetic acid + NH3
show the reaction diagram
-
-
acetylphosphate + H2O = acetate + phosphate
show the reaction diagram
-
-
oxaloacetate + H2O = oxalate + acetate
show the reaction diagram
-
2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate
show the reaction diagram
-
-
(2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + acetate
show the reaction diagram
-
-
acetylpyruvate + H2O = acetate + pyruvate
show the reaction diagram
-
iodoacetic acid + H2O = acetic acid + iodide + H+
show the reaction diagram
-
malonate + H+ = acetate + CO2
show the reaction diagram
-
-
4-coumarate + H2O = 4-hydroxybenzaldehyde + acetate
show the reaction diagram
-
-
citrate = acetate + oxaloacetate
show the reaction diagram
salutaridinol 7-O-acetate = thebaine + acetate
show the reaction diagram
-
-
ADP + phosphate + acetyl-CoA = ATP + acetate + CoA
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (155 results)

top print hide
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
24-methylenepollinastanone + NADPH + acetate = 24-methylenepollinastanol + NADP+
show the reaction diagram
-
(R,S)-mevaldehyde + acetate = ?
show the reaction diagram
-
acetate + N,N-dimethyl-4-nitrosoaniline = ? + 4-(hydroxylamino)-N,N-dimethylaniline
show the reaction diagram
-
NADH + acetate = NAD+ + ?
show the reaction diagram
-
acetate + NADH + H+ = acetaldehyde + NAD+ + H2O
show the reaction diagram
-
arsenate + acetate = arsenite + ?
show the reaction diagram
-
selenate + acetate = selenite + H2O + CO2
show the reaction diagram
-
acetate + ATP = acetyl phosphate + ADP
show the reaction diagram
-
malonyl-CoA + acetate = acetyl-CoA + malonate
show the reaction diagram
-
acetate + pyruvate = citramalate
show the reaction diagram
-
sucrose + acetate = D-fructose + 1-O-acetyl-alpha-D-glucopyranose
show the reaction diagram
-
L-cystathionine + acetate = O-acetyl-L-serine + L-homocysteine
show the reaction diagram
-
L-cystathionine + acetate = O-acetyl-L-homoserine + L-cysteine
show the reaction diagram
-
ATP + acetate = ADP + acetyl phosphate
show the reaction diagram
-
ATP + NH3 + acetate = ADP + ?
show the reaction diagram
ATP + acetate = ADP + acetyl phosphate
show the reaction diagram
-
ATP + acetate = ADP + acetyl phosphate
show the reaction diagram
-
glutaryl-CoA + acetate = glutarate + acetyl-CoA
show the reaction diagram
-
acetate + oxalyl-CoA = acetyl-CoA + oxalate
show the reaction diagram
-
acetate + succinyl-CoA = acetyl-CoA + succinate
show the reaction diagram
-
2-chloro-5,5-dimethyl-1,3-cyclohexanedimedon + Br- + acetic acid + H2O2 = 2-chloro-2-bromo-5,5-dimethyl-1,3-cyclohexanedimedon + acetic acid + H2O
show the reaction diagram
-
D-glucosamine 6-phosphate + acetate = N-acetyl-D-glucosamine 6-phosphate + H2O
show the reaction diagram
-
acetate + oxaloacetate = citrate
show the reaction diagram
acetate = 2-oxoethanal + H2O
show the reaction diagram
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
acyl-carrier protein + acetate + ATP = acetyl-acyl carrier protein + AMP + diphosphate
show the reaction diagram
-
acetate + ATP + coenzyme A = acetyl-CoA + AMP + diphosphate
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
-
ATP + acetate + CoA = ADP + phosphate + acetyl-CoA
show the reaction diagram
ATP + acetate + N1-(5-phospho-beta-D-ribosyl)glycinamide = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4482 results)

top print hide
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-lactate + O2 = acetate + CO2 + H2O
show the reaction diagram
-
acetaldehyde + acceptor + H2O = acetic acid + reduced acceptor
show the reaction diagram
-
(2R)-hydroxypropylphosphonate + O2 = 2-oxopropylphosphonate + hydroxymethylphosphonate + acetate
show the reaction diagram
-
(R)-1-hydroxyethylphosphonic acid + O2 = acetate + phosphate
show the reaction diagram
-
-
17alpha-Hydroxyprogesterone + NADPH + O2 = androstenedione + acetate + NADP+ + H2O
show the reaction diagram
7389, -
-
acetaldehyde + H2O + O2 = acetic acid + H2O2
show the reaction diagram
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
acetaldehyde + NAD(P)+ + H2O = acetate + NAD(P)H + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
390324, -
-
acetaldehyde + NAD+ + H2O = acetate + NADH + 2 H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + NAD+ + H2O = acetate + NADH + H+
show the reaction diagram
-
-
acetaldehyde + 2,6-dichlorophenolindophenol = acetate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
acetaldehyde + H2O + O2 = acetate + H2O2
show the reaction diagram
-
-
acetaldehyde + O2 + H2O = acetate + H2O2
show the reaction diagram
-
-
acetaldehyde + H2O = acetate + ethanol
show the reaction diagram
-
acetaldehyde + 2,6-dichlorophenolindophenol + H2O = acetate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
harderoheme IV + peracetic acid = ? + CO2 + 2 acetate
show the reaction diagram
-
-
Gly + H2O + O2 = acetate + NH3 + H2O2
show the reaction diagram
-
selenate + lactate = selenite + H2O + acetate + HCO3-
show the reaction diagram
644812, -
-
acetyl-CoA + malonate = malonyl-CoA + acetate
show the reaction diagram
-
-
acetyl-CoA + H2O = acetate + CoA
show the reaction diagram
-
malonate + acetyl-[acyl-carrier protein] = acetate + malonyl-[acyl-carrier protein]
show the reaction diagram
-
-
p-nitrophenylacetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
acetyl-CoA + cyclohexane-1-carboxylate = acetate + cyclohexane-1-carbonyl-CoA
show the reaction diagram
-
-
1-O-alkyl-2-acetyl-sn-glycerol-3-phosphocholine + H2O = 1-O-alkyl-2-lyso-sn-glycerol-3-phosphocholine + acetate
show the reaction diagram
-
acetyl-CoA + H2O = CoA + acetate
show the reaction diagram
-
acetyl-CoA + alcohol = CoA + acetate
show the reaction diagram
-
-
acetyl-CoA + H2O = acetate + CoA
show the reaction diagram
488098, -
-
acetyl-CoA + H2O = acetate + CoA
show the reaction diagram
-
-
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate
show the reaction diagram
-
-
O-acetyl-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH = [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + acetate
show the reaction diagram
-
O3-acetyl-L-serine + isoxazolin-5-one = 3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate
show the reaction diagram
-
-
O3-acetyl-L-serine + isoxazolin-5-one = 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate
show the reaction diagram
-
-
O-acetyl-L-homoserine + L-cysteine = L-cystathionine + acetate
show the reaction diagram
-
-
2 O3-acetyl-L-serine + 2 uracil = 3-(uracil-1-yl)-L-alanine + 3-(uracil-3-yl)-L-alanine + 2 acetate
show the reaction diagram
-
O-acetyl-L-serine + hydroxyurea = O-ureido-L-serine + acetate
show the reaction diagram
-
-
acetyl-phosphate + D-fructose 6-phosphate = acetate + D-fructose 1,6-bisphosphate
show the reaction diagram
-
-
acetyl-phosphate + N-acetyl-alpha-D-galactosamine = acetate + N-acetyl-alpha-D-galactosamine 1-phosphate
show the reaction diagram
-
-
acetylphosphate + inosine = acetate + IMP
show the reaction diagram
-
-
ADP + acetyl phosphate = ATP + acetate
show the reaction diagram
-
oxalate + acetyl-CoA = oxalyl-CoA + acetate
show the reaction diagram
-
-
acetyl-CoA + succinate = acetate + succinyl-CoA
show the reaction diagram
-
-
acetyl-CoA + malonate = acetate + malonyl-CoA
show the reaction diagram
-
succinate + acetyl-CoA = acetate + succinyl-CoA
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
methyl acetate + H2O = methanol + acetate
show the reaction diagram
-
-
4-nitrophenylacetate + H2O = 4-nitrophenol + acetic acid
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
6-acetyl-D-glucose + H2O = glucose + acetate
show the reaction diagram
-
triacetin + H2O = acetate + diacetin
show the reaction diagram
-
methyl acetate = acetate + methanol
show the reaction diagram
-
hexadecanyl acetate + H2O = hexadecanol + acetate
show the reaction diagram
-
-
5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
all-trans-retinyl acetate + H2O = all-trans-retinol + acetate
show the reaction diagram
-
-
3,4-diacetoxybutynylbithiophene + H2O = 3-hydroxy-4-acetoxybutynylbithiophene + acetate
show the reaction diagram
643846, -
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
acetyl-CoA + H2O = CoA + acetate
show the reaction diagram
-
[citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate
show the reaction diagram
-
acetyl-CoA + H2O = CoA + acetate
show the reaction diagram
-
-
acetyl-CoA + H2O = acetate + CoA
show the reaction diagram
-
-
acetyl-CoA + H2O = acetate + CoA
show the reaction diagram
-
-
S-acetylglutathione + H2O = glutathione + acetate
show the reaction diagram
-
phenyl acetate + H2O = phenol + acetate
show the reaction diagram
-
Phosphonoacetate + H2O = acetate + phosphate
show the reaction diagram
-
alpha-naphthylacetate + H2O = alpha-naphthol + acetate
show the reaction diagram
-
-
p-nitrophenyl acetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
N2-acetyl-L-2,4-diaminobutanoate + H2O = L-2,4-diaminobutanoate + acetate
show the reaction diagram
-
-
N-acetyl-L-aspartate + H2O = acetate + L-aspartate
show the reaction diagram
-
-
acetyl agmatine + H2O = acetic acid + agmatine
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
N-acetylputrescin + H2O = putrescine + acetate
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
acetyl-L-glutamic acid + H2O = acetate + L-glutamate
show the reaction diagram
-
N-Acetyl-D-Asp + H2O = acetate + D-Asp
show the reaction diagram
-
-
(S)-N-acetyl-1-phenylethylamine + H2O = (S)-1-phenylethylamine + acetate
show the reaction diagram
-
N-benzylacetamide + H2O = acetate + benzylamine
show the reaction diagram
-
-
N-acetyl cephalosporin C + H2O = acetate + cephalosporin C
show the reaction diagram
-
-
peptidoglycan + H2O = deacetylated peptidoglycan + acetate
show the reaction diagram
-
-
acetyl adenylate + H2O = acetic acid + AMP
show the reaction diagram
-
-
oxaloacetate + H2O = oxalate + acetate
show the reaction diagram
-
2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate
show the reaction diagram
-
-
(2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + acetate
show the reaction diagram
-
-
acetylpyruvate + H2O = acetate + pyruvate
show the reaction diagram
-
-
acetylpyruvate + H2O = acetate + pyruvate
show the reaction diagram
-
-
acetylpyruvate + H2O = acetate + pyruvate
show the reaction diagram
-
phenyl acetate + H2O = phenol + acetate
show the reaction diagram
-
-
3-Fluoropyruvate = acetate + F- + CO2
show the reaction diagram
-
malonate + H+ = acetate + CO2
show the reaction diagram
-
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
-
4-coumarate + H2O = 4-hydroxybenzaldehyde + acetate
show the reaction diagram
-
-
citramalate = acetate + pyruvate
show the reaction diagram
-
2-oxoethanal + H2O = acetate
show the reaction diagram
-
salutaridinol 7-O-acetate = thebaine + acetate
show the reaction diagram
-
-
O-acetyl-L-serine + H2O = acetate + pyruvate + NH3
show the reaction diagram
-
-
O-acetyl-L-serine + H2O = acetate + pyruvate + NH3
show the reaction diagram
-
ADP + phosphate + acetyl-CoA = ATP + acetate + CoA
show the reaction diagram
-
malonate + H+ = acetate + CO2
show the reaction diagram
-
-
acetyl phosphate + H2O = acetate + phosphate
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (108 results)

top print hide
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50 mM: activates, 100 mM: 100% increase in activity at pH 4
-
acts as a cofactor
-
form 1, AE-I, activates below pH 6.0
-
the oxidizing activity of CueO for ABTS, reaction of EC 1.10.3.2, is enhanced by the addition of up to 300 mM acetate ion, although it decreases at higher concentrations
-
activity is upregulated during photoheterotrophic growth on acetate compared to the activities during growth on succinate
-
25 mM, 2.3fold activation
-
activates
activation
-
stimulates alanine transamination, inhibits lysine transamination
-
as Na or K salt continues to activate at concentrations above 200 mM
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
-
0.05 M, about 15% activation
-
activation
about 200% activity at 2 mM
-
in pH-controlled cultures, the addition of 20 mM acetate promotes a more vigorous solventogenic fermentation
-
if a carboxylic acid, such as acetate, is omitted from the reaction using the pure enzyme, no enzyme activity is found. As soon as a carboxylic acid is added, the decarboxylation starts immediately. The enzyme activity is increased with the number of carbon atoms, rising from formate to butyrate. Above four carbon atoms, the activity decreases. Pimelate, butyrate and propionate are the strongest activators
-
activity of the ICL promoter is significantly upregulated during growth on acetate
growth of the mcl1::kan mutant on acetate is not rescued by the addition of glyoxylate, the mutant growth rates are comparable to those of the wild type on substrates downstream of the proposed metabolic block, i.e., malate and propionate plus bicarbonate
-
0.2 M, activation
activity is higher in extracts of cells grown on acetate
-
2fold activation, maximum between 0.5 and 0.7 M
-
0.030 mM
-
activation of mutant K202A
-

Inhibitor in Enzyme-catalyzed Reactions (513 results)

top print hide
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
slight inhibition at 5 mM
-
slight inhibition
-
about 20% residual activity at 8% (v/v) acetic acid
-
38% inhibition at 5 mM
-
inhibits by hindering the tod gene expression
-
92 mM, pH 8, very slight inhibition
-
50% inhibition at 0.123 M
-
competitive inhibition
-
the presence of acetate and succinate in the growth medium results in a 50% reduction in inducible GCV enzyme activity
-
competitive
-
slight
-
80% inhibition at 250 mM, with glycine
-
inhibition in decreasing order: fumarate, succinate, citrate, acetate
-
weak inhibition of wild-type activity, no effect on the activity of the H334G mutant
-
26% inhibition
-
stimulates alanine transamination, inhibits lysine transamination
-
inhibitor/substrate ratio = 3, 20% inhibition
-
noncompetitive to glucose
-
weak, in vivo and in vitro
-
inhibition by preincubation with MgCl2, ADP, AlCl3, NaF, and acetate. When MgCl2, ADP, and acetate are omitted from the preincubation mixture, there is no detectable loss of activity; inhibition of acetate kinase by preincubation with MgCl2, ADP, AlCl3, NaF, and acetate (all of the components are necessary for maximum inhibition)
completely inhibits activity
no activity in Tris-citrate and only minimal activity in acetate buffer
-
inactivates at 50% w/v
-
1%, 86% inhibition
-
inhibits the enzyme in colonic tissue, but not in plasma
product inhibition
-
slight inhibition at 3.2 mM
-
8 mM: 88% of activity compared to H2O
-
inhibitory at 20 mM
-
97.1% inhibition at 10 mM
-
competitive to bicarbonate
-
2.0 M, 50% inhibition of ATP-diphosphate exchange
-
1.3 M, 50% inhibition of ATP-diphosphate exchange
-
inhibition of wild-type enzyme
-
modest inhibitory effect
-

Metals and Ions (2 results)

top print hide
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
the acetate ion binds close to Mg2+, and it interacts with two coordinating water molecules
-
anions that favor activity in decreasing order: acetate, HCOO-, Cl-, at 50 mM K+
-

3D Structure of Enzyme-Ligand-Complex (PDB) (26356 results)

top print hide
EC NUMBER
ENZYME 3D STRUCTURE