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Ligand dTDP-4-amino-4,6-dideoxy-D-galactose

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.210

acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose

719706

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2.6.1.59

dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate

636976

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Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.210

acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose

719706

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2.6.1.59

dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate

636976

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Product in Enzyme-catalyzed Reactions (7 results)

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Show Product (7 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.6.1.33

dTDP-4-dehydro-6-deoxy-D-glucose + glycine = dTDP-4-amino-4,6-dideoxy-D-galactose + glyoxylate

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2.6.1.33

dTDP-4-dehydro-6-deoxy-D-glucose + L-alanine = dTDP-4-amino-4,6-dideoxy-D-galactose + pyruvate

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2.6.1.33

dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate

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2.6.1.33

dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamine = dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutamine

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2.6.1.59

dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate

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2.6.1.59

dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamine = dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutaramate

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2.6.1.59

TDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate

636976

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2.6.1.33

4 entries

2.6.1.59

3 entries

Enzyme Kinetic Parameters

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.6.1.59

0.16

-

pH 7.0, 38°C

636976

References & Links

Literature References (2)

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Show Reference (2 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

636976

4928644

Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis

1971

Ohashi, H.; Matsuhashi, M.; Matsuhashi, S.

J. Biol. Chem.

246

2325-2330

719706

16855251

Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis

2006

Hung, M.N.; Rangarajan, E.; Munger, C.; Nadeau, G.; Sulea, T.; Matte, A.

J. Bacteriol.

188

5606-5617

Links to other databases for dTDP-4-amino-4,6-dideoxy-D-galactose

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Show Links (1 entry)

ChEBI

PubChem

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