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Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein
2004
Brule, H.; Elliott, M.; Redlak, M.; Zehner, Z.E.; Holmes, W.M.
Biochemistry
43
9243-9255
Characterization of Streptococcus pneumoniae TrmD, a tRNA methyltransferase essential for growth
2004
O'Dwyer, K.; Watts, J.M.; Biswas, S.; Ambrad, J.; Barber, M.; Brule, H.; Petit, C.; Holmes, D.J.; Zalacain, M.; Holmes, W.M.
J. Bacteriol.
186
2346-2354
The substrate specificity of tRNA (m1G37) methyltransferase (TrmD) from Aquifex aeolicus
2006
Takeda, H.; Toyooka, T.; Ikeuchi, Y.; Yokobori, S.; Okadome, K.; Takano, F.; Oshima, T.; Suzuki, T.; Endo, Y.; Hori, H.
Genes Cells
11
1353-1365
Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase
2007
Lee, C.; Kramer, G.; Graham, D.E.; Appling, D.R.
J. Biol. Chem.
282
27744-27753
Distinct determinants of tRNA recognition by the TrmD and Trm5 methyl transferases
2007
Christian, T.; Hou, Y.M.
J. Mol. Biol.
373
623-632
Control of catalytic cycle by a pair of analogous tRNA modification enzymes
2010
Christian, T.; Lahoud, G.; Liu, C.; Hou, Y.M.
J. Mol. Biol.
400
204-217
Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5
2010
Christian, T.; Lahoud, G.; Liu, C.; Hoffmann, K.; Perona, J.J.; Hou, Y.M.
RNA
16
2484-2492
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor
2011
Lahoud, G.; Goto-Ito, S.; Yoshida, K.; Ito, T.; Yokoyama, S.; Hou, Y.M.
RNA
17
1236-1246
Recognition of guanosine by dissimilar tRNA methyltransferases
2012
Sakaguchi, R.; Giessing, A.; Dai, Q.; Lahoud, G.; Liutkeviciute, Z.; Klimasauskas, S.; Piccirilli, J.; Kirpekar, F.; Hou, Y.M.
RNA
18
1687-1701
TRMT5 mutations cause a defect in post-transcriptional modification of mitochondrial tRNA associated with multiple respiratory-chain deficiencies
2015
Powell, C.A.; Kopajtich, R.; DSouza, A.R.; Rorbach, J.; Kremer, L.S.; Husain, R.A.; Dallabona, C.; Donnini, C.; Alston, C.L.; Griffin, H.; Pyle, A.; Chinnery, P.F.; Strom, T.M.; Meitinger, T.; Rodenburg, R.J.; Schottmann, G.; Schuelke, M.; Romain, N.; Haller, R.G.; Ferrero, I.; Haack, T.B.; Taylor, R.W.; Pr, P.r.o.
Am. J. Hum. Genet.
97
319-328
A divalent metal ion-dependent N1-methyl transfer to G37-tRNA
2014
Sakaguchi, R.; Lahoud, G.; Christian, T.; Gamper, H.; Hou, Y.M.
Chem. Biol.
21
1351-1360
The temperature sensitivity of a mutation in the essential tRNA modification enzyme tRNA methyltransferase D (TrmD)
2013
Masuda, I.; Sakaguchi, R.; Liu, C.; Gamper, H.; Hou, Y.M.
J. Biol. Chem.
288
28987-28996
Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD
2015
Ito, T.; Masuda, I.; Yoshida, K.; Goto-Ito, S.; Sekine, S.; Suh, S.W.; Hou, Y.M.; Yokoyama, S.
Proc. Natl. Acad. Sci. USA
112
E4197-E4205
Conservation of structure and mechanism by Trm5 enzymes
2013
Christian, T.; Gamper, H.; Hou, Y.M.
RNA
19
1192-1199
Targeting the bacterial epitranscriptome for antibiotic development discovery of novel tRNA-(N1G37) methyltransferase (TrmD) inhibitors
2019
Zhong, W.; Koay, A.; Ngo, A.; Li, Y.; Nah, Q.; Wong, Y.H.; Chionh, Y.H.; Ng, H.Q.; Koh-Stenta, X.; Poulsen, A.; Foo, K.; McBee, M.; Choong, M.L.; El Sahili, A.; Kang, C.; Matter, A.; Lescar, J.; Hill, J.; Dedon, P.
ACS Infect. Dis.
5
326-335
Backbone resonance assignment for the full length tRNA-(N1G37) methyltransferase of Pseudomonas aeruginosa
2019
Li, Y.; Zhong, W.; Koay, A.Z.; Ng, H.Q.; Nah, Q.; Wong, Y.H.; Hill, J.; Lescar, J.; Dedon, P.C.; Kang, C.
Biomol. NMR Assign.
13
327-332
Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase
2019
Li, Y.; Zhong, W.; Koay, A.Z.; Ng, H.Q.; Koh-Stenta, X.; Nah, Q.; Lim, S.H.; Larsson, A.; Lescar, J.; Hill, J.; Dedon, P.C.; Kang, C.
Biomol. NMR Assign.
13
49-53
Trm5 and TrmD two enzymes from distinct origins catalyze the identical tRNA modification, m1G37
2017
Goto-Ito, S.; Ito, T.; Yokoyama, S.
Biomolecules
7
32
Transfer RNA methyltransferases with a SpoU-TrmD (SPOUT) fold and their modified nucleosides in tRNA
2017
Hori, H.
Biomolecules
7
E23
TrmD A methyl transferase for tRNA methylation with m1G37
2017
Hou, Y.; Matsubara, R.; Takase, R.; Masuda, I.; Sulkowska, J.
Enzymes
41
89-115
Codon-specific translation by m1G37 methylation of tRNA
2019
Hou, Y.; Masuda, I.; Gamper, H.
Front. Genet.
10
713
A hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function
2018
Zhou, M.; Xue, L.; Chen, Y.; Li, H.; He, Q.; Wang, B.; Meng, F.; Wang, M.; Guan, M.X.
J. Biol. Chem.
293
1425-1438
Development of inhibitors against Mycobacterium abscessus tRNA (m1G37) methyltransferase (TrmD) using fragment-based approaches
2019
Whitehouse, A.J.; Thomas, S.E.; Brown, K.P.; Fanourakis, A.; Chan, D.S.; Libardo, M.D.J.; Mendes, V.; Boshoff, H.I.M.; Floto, R.A.; Abell, C.; Blundell, T.L.; Coyne, A.G.
J. Med. Chem.
62
7210-7232
Thienopyrimidinone derivatives that inhibit bacterial tRNA (guanine37-N1)-methyltransferase (TrmD) by restructuring the active site with a tyrosine-flipping mechanism
2019
Zhong, W.; Pasunooti, K.K.; Balamkundu, S.; Wong, Y.H.; Nah, Q.; Gadi, V.; Gnanakalai, S.; Chionh, Y.H.; McBee, M.E.; Gopal, P.; Lim, S.H.; Olivier, N.; Buurman, E.T.; Dick, T.; Liu, C.F.; Lescar, J.; Dedon, P.C.
J. Med. Chem.
62
7788-7805
Kinetic analysis of tRNA methyltransferases
2015
Hou, Y.M.; Masuda, I.
Methods Enzymol.
560
91-116
Methyl transfer by substrate signaling from a knotted protein fold
2016
Christian, T.; Sakaguchi, R.; Perlinska, A.; Lahoud, G.; Ito, T.; Taylor, E.; Yokoyama, S.; Sulkowska, J.; Hou, Y.
Nat. Struct. Mol. Biol.
23
941-948
AtTrm5a catalyses 1-methylguanosine and 1-methylinosine formation on tRNAs and is important for vegetative and reproductive growth in Arabidopsis thaliana
2019
Jin, X.; Lv, Z.; Gao, J.; Zhang, R.; Zheng, T.; Yin, P.; Li, D.; Peng, L.; Cao, X.; Qin, Y.; Persson, S.; Zheng, B.; Chen, P.
Nucleic Acids Res.
47
883-898
Evolution of tRNAPhe imG2 methyltransferases involved in the biosynthesis of wyosine derivatives in Archaea
2016
Urbonavicius, J.; Rutkiene, R.; Lopato, A.; Tauraite, D.; Stankeviciute, J.; Aucynaite, A.; Kaliniene, L.; van Tilbeurgh, H.; Meskys, R.
RNA
22
1871-1883
Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
2019
Jaroensuk, J.; Wong, Y.H.; Zhong, W.; Liew, C.W.; Maenpuen, S.; Sahili, A.E.; Atichartpongkul, S.; Chionh, Y.H.; Nah, Q.; Thongdee, N.; McBee, M.E.; Prestwich, E.G.; DeMott, M.S.; Chaiyen, P.; Mongkolsuk, S.; Dedon, P.C.; Lescar, J.; Fuangthong, M.
RNA
25
1481-1496
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