Ligand GTP

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Basic Ligand Information

Molecular Structure
Picture of GTP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H16N5O14P3
GTP
XKMLYUALXHKNFT-UUOKFMHZSA-N
Synonyms:
5'-GTP, guanosine-5'-triphosphate, guanosine 5'-triphosphate, guanosine triphosphate, pppG, rGTP

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (196 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cob(I)alamin + GTP + H2O + H+ = guanosylcobalamin + diphosphate + phosphate
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GTP + 5-hydroxy-L-lysine = GDP + O-phosphohydroxy-L-lysine
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GTP + AMP = GDP + ADP
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GTP + nicotinamide ribonucleotide = nicotineamide guanine dinucleotide + diphosphate
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GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose
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GTP + GTP = diphosphate + P1,P4-bis(5'-guanosyl)tetraphosphate
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GTP + adenosylcobinamide phosphate = diphosphate + adenosylcobinamide-GDP
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(2S)-2-phospholactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate
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D-glycero-D-alpha-manno-heptose 1-phosphate + GTP = GDP-D-glycero-D-alpha-manno-heptose + diphosphate
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GTP + MoO2(OH)Dtpp-mP = diphosphate + MoO2(OH)Dtpp-mGDP
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GTP + valienol 1-phosphate = diphosphate + GDP-valienol
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GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + diphosphate
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GTP + H2O = GDP + phosphate
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GTP + 2 H2O = GMP + 2 phosphate
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GTP + H2O = GMP + diphosphate
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GTP + H2O = GMP + diphosphate
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GTP = cyclic pyranopterin phosphate + diphosphate
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GTP + H2O = GDP + phosphate
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GTP + H2O + a kinesin associated with a microtubule at position n = GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
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GTP + acetate + CoA = GDP + phosphate + acetyl-CoA
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L-glutamate + GTP + coenzyme F420-0 = GDP + phosphate + coenzyme gamma-F420-1
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GTP + tetrahydromethanopterin + L-glutamate = GDP + phosphate + 5,6,7,8-tetrahydrosarcinapterin
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GTP + RNA 3'-terminal-phosphate = GMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate
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GTP + (deoxyribonucleotide)n + (deoxyribonucleotide)m = GMP + diphosphate + (deoxyribonucleotide)n+m
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GTP + H2O = ?
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In Vivo Product in Enzyme-catalyzed Reactions (39 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDP + 3-phospho-D-glyceroyl 1-phosphate = GTP + 3-phospho-D-glycerate
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ATP + GDP = ADP + GTP
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guanosine 3'-diphosphate 5'-triphosphate + H2O = GTP + diphosphate
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diphosphate + GDP-mannose = GTP + alpha-D-mannose 1-phosphate
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GDP + phosphate + succinyl-CoA = GTP + succinate + CoA
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Substrate in Enzyme-catalyzed Reactions (759 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GTP + formate = dGTP + CO2 + H2O
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Photinus luciferin + O2 + GTP = adenosine 5'-P1-tetraphospho-P4-5'''-guanosine
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GTP + reduced thioredoxin = dGTP + oxidized thioredoxin + H2O
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peroxiredoxin-(S-hydroxy-S-oxocysteine) + GTP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + GDP + phosphate + R-S-S-R
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[elongator tRNAMet]-cytidine34 + GTP + acetyl-CoA = [elongator tRNAMet]-N4-acetylcytidine34 + GDP + phosphate + coenzyme A
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GTP + citrate + CoA = GDP + phosphate + acetyl-CoA + oxaloacetate
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dimethylallyl diphosphate + GTP = ?
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GTP + L-methionine + H2O = S-guanosyl-L-methionine + phosphate + diphosphate
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GTP + D-glucose = GDP + D-glucose 6-phosphate
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GTP + beta-D-fructose 6-phosphate = GDP + beta-D-fructose 2,6-bisphosphate
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GTP + D-fructose 6-phosphate = GDP + D-fructose 1,6-bisphosphate
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GTP + D-gluconate = GDP + 6-phospho-D-gluconate
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GTP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(beta-D-1,6-)-2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl beta-phosphate = GDP + 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
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GTP + ceramide = GDP + ceramide 1-phosphate
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GTP + D-tagatose 6-phosphate = GDP + D-tagatose 1,6-bisphosphate
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GTP + D-ribose = GDP + D-ribose 5-phosphate
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GTP + N-acetyl-alpha-D-glucosamine = GDP + N-acetyl-alpha-D-glucosamine 1-phosphate
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GTP + L-seryl-tRNASec = GDP + O-phospho-L-seryl-tRNASec
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3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-[[(3R)-3-hydroxypentadecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose + GTP = 3-deoxy-4-O-phosphono-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-[[(3R)-3-hydroxypentadecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose + GDP
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GTP + pantoate = GDP + 4-phosphopantoate
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GTP + beta-D-ribosylnicotinate = GDP + nicotinate beta-D-ribonucleotide
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GTP + maltose = GDP + maltose 1-phosphate
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GTP + phytol = GDP + phytyl phosphate
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D-ribulose 5-phosphate + GTP = D-ribulose 1,5-diphosphate + GDP
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GTP + D-glucose = GDP + D-glucose 6-phosphate
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cytidine + GTP = CMP + GDP
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GTP + (2E,6E)-farnesol = GDP + (2E,6E)-farnesyl phosphate
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GTP + riboflavin = GTP + riboflavin 5'-phosphate
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GTP + D-glyceraldehyde = GDP + D-glyceraldehyde-3-phosphate
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GTP + dihydroxyacetone = GDP + dihydroxyacetone phosphate
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GTP + D-fructose = ?
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GTP + glycerol = GDP + glycerol 3-phosphate
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GTP + (R)-glycerate = GDP + 3-phospho-(R)-glycerate
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GTP + choline = GDP + choline phosphate
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GTP + D-fructose = GDP + D-fructose 6-phosphate
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GTP + 2-dehydro-3-deoxy-D-gluconate = GDP + 6-phospho-2-dehydro-3-deoxy-D-gluconate
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GTP + 5-hydroxy-2-methylpyrimidine = GDP + 2-methyl-5-phosphopyrimidine
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GTP + 4-methyl-5-(2-hydroxyethyl)thiazole = GDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole
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GTP + 6-deoxy-L-galactose = GDP + 6-deoxy-L-galactose 1-phosphate
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GTP + D-arabinose = GDP + D-arabinose 5-phosphate
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GTP + D-fructose 1-phosphate = GDP + D-fructose 1,6-bisphosphate
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GTP + N-acetyl-D-glucosamine = GDP + N-acetyl-D-glucosamine 6-phosphate
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GTP + D-galactose = GDP + alpha-D-galactose 1-phosphate
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GTP + myo-inositol = GDP + myo-inositol 1-phosphate
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GTP + 1-phosphatidyl-1D-myo-inositol = GDP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
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GTP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = GDP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
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GTP + D-glucosamine = GDP + D-glucosamine 6-phosphate
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GTP + cellobiose = GDP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose
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GTP + NADH = GDP + NADPH
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GTP + sphinganine = GDP + sphinganine 1-phosphate
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GTP + geranylgeraniol = GDP + geranylgeranyl phosphate
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GTP + rhodopsin = GDP + phosphorhodopsin
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GTP + beta-adrenergic receptor = GDP + phospho-beta-adrenergic receptor
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GTP + phosphorylase b = GDP + phosphorylase a
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GTP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] = GDP + ?
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GTP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = GDP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
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GTP + acetate = GDP + acetyl phosphate
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GTP + 3-phospho-D-glycerate = GDP + 3-phospho-D-glyceroyl 1-phosphate
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GTP + L-glutamate = GDP + L-glutamate 5-phosphate
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GTP + isobutanoate = GDP + isobutanoyl phosphate
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GTP + propanoate = GDP + propanoyl phosphate
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GTP + 3-phospho-D-glycerate = GDP + 1,3-diphosphoglycerate
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GTP + L-aspartate = GDP + 4-phospho-L-aspartate
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GTP + formate = GDP + formyl phosphate
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GTP + L-arginine = GDP + Nomega-phospho-L-arginine
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GTP + (R,S)-5-phosphomevalonate = GDP + (R,S)-5-diphosphomevalonate
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GTP + AMP = GDP + ADP
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GTP + dAMP = GDP + dADP
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GTP + dTMP = GDP + dTDP
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GTP + UMP = GDP + UDP
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GTP + D-ribose 5-phosphate = GMP + 5-phospho-alpha-D-ribose 1-diphosphate
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GTP + thiamine = GMP + thiamine diphosphate
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GTP + FMN = diphosphate + flavin guanidine dinucleotide
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GTP + alpha-D-glucose 1-phosphate = diphosphate + GDP-glucose
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GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose
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GTP + tobramycin = diphosphate + 2''-adenylyltobramycin
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GTP + adenosylcobinamide phosphate = diphosphate + adenosylcobinamide-GDP
show the reaction diagram
(2S)-2-phospholactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate
show the reaction diagram
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D-glycero-D-alpha-manno-heptose 1-phosphate + GTP = GDP-D-glycero-D-alpha-manno-heptose + diphosphate
show the reaction diagram
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RNA + GTP = RNA+1 + diphosphate
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3 GTP = ?
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5'-triphospho-mRNA + GTP = diphosphate + guanosine 5'-tetraphospho-mRNA
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GTP + valienol 1-phosphate = diphosphate + GDP-valienol
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GTP + n GTP = G(pG)n + n diphosphate
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tRNA-uridine + GTP = adenylated-trNA-uridine + diphosphate
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GTP + H2O = guanine + D-ribose-5-triphosphate
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GTP + H2O = ?
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GTP + H2O = ?
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GTP + H2O = GDP + phosphate
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GTP + H2O = ?
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glucose + GTP = glucose 6-phosphate + GDP
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GTP + H2O = ?
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GTP + H2O = guanosine + triphosphate
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GTP + dihydrouracil + H2O = ?
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GTP + H2O = ?
show the reaction diagram
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GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + diphosphate
show the reaction diagram
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GTP + H2O = ?
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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GTP + H2O = GMP + diphosphate
show the reaction diagram
GTP + H2O = GDP + diphosphate
show the reaction diagram
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GTP + H2O = GMP + diphosphate
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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GTP + H2O = GDP + phosphate
show the reaction diagram
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