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Ligand N-methylguanosine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

6.3.4.2

-

674909

-

Enzyme Kinetic Parameters

IC₅₀ Value (2 results)

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Show IC50 Value (2 entries)

EC NUMBER

IC50 VALUE

IC50 VALUE MAXIMUM

COMMENTARY

LITERATURE

6.3.4.2

0.17

-

IC50 for inhibition of Gln-dependent CTP formation

674909

6.3.4.2

0.23

-

IC50 for inhibition of NH3-dependent CTP formation

674909

6.3.4.2

2 entries

References & Links

Literature References (1)

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Show Reference (1 entry)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

674909

18003612

Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are Lax

2007

Lunn, F.A.; Macdonnell, J.E.; Bearne, S.L.

J. Biol. Chem.

283

2010-2020

Links to other databases for N-methylguanosine

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Show Links (1 entry)