Ligand galactaric acid

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Basic Ligand Information

Molecular Structure
Picture of galactaric acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H10O8
galactaric acid
DSLZVSRJTYRBFB-DUHBMQHGSA-N
Synonyms:
D-galactarate, D-galactaric acid, galactarate, meso-galactarate, meso-galactaric acid


Show all pahtways known for Show all BRENDA pathways known for galactaric acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
5-O-caffeoylquinic acid + galactaric acid = quinate + caffeoylgalactaric acid
-

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
5-O-caffeoylquinic acid + galactaric acid = quinate + caffeoylgalactaric acid
-
show the reaction diagram
galactarate = 2-oxo-D-threo-4,5-dihydroxyadipate + H2O
-
show the reaction diagram
galactarate = ?
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
induces KGSADH-II
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
pH 8.0, 30°C
6.8
-
-
22
-
at pH 7.9 and 22°C
0.12
-
mutant H45Q, in 50 mM Hepes, pH 8.0, 5 mM MgCl2
0.0013
-
mutant Y90F, in 50 mM Hepes, pH 8.0, 5 mM MgCl2
0.0061
-
pH 8, 25°C
4.8
-
pH 8.0, 25°C
3.6
-
pH 8.0, 25°C, His6-tagged recombinant enzyme
4.8
-
wild-type, in 50 mM Hepes, pH 8.0, 5 mM MgCl2
6.8
-

KM Value (13 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
pH 8.5, 38°C
0.42
-
pH 8.0, 30°C
0.62
-
at pH 7.9 and 22°C
0.08
-
mutant H45Q, in 50 mM Hepes, pH 8.0, 5 mM MgCl2
4.4
-
mutant Y90F, in 50 mM Hepes, pH 8.0, 5 mM MgCl2
2
-
pH 8, 25°C
0.38
-
pH 8.0, 25°C
0.33
-
pH 8.0, 25°C, His6-tagged recombinant enzyme
0.38
-
wild-type, in 50 mM Hepes, pH 8.0, 5 mM MgCl2
0.62
-

References & Links

Links to other databases for galactaric acid

ChEBI
PubChem
ChEBI
PubChem